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G2505

Sigma-Aldrich

N-Glutaryl-L-phenylalanine p-nitroanilide

protease substrate

Sinônimo(s):

Glutaryl-L-phenylalanine 4-nitroanilide

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About This Item

Fórmula empírica (Notação de Hill):
C20H21N3O6
Número CAS:
5800-34-0
Peso molecular:
399.40
Beilstein:
2919832
Número CE:
227-351-4
Número MDL:
MFCD00038362
Código UNSPSC:
12352204
ID de substância PubChem:
24895096
NACRES:
NA.83

Ensaio

≥98% (HPLC)

forma

powder

solubilidade

methanol with 1 M NH4OH: 50 mg/mL, clear to slightly hazy

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC(=O)CCCC(=O)N[C@@H](Cc1ccccc1)C(=O)Nc2ccc(cc2)[N+]([O-])=O

InChI

1S/C20H21N3O6/c24-18(7-4-8-19(25)26)22-17(13-14-5-2-1-3-6-14)20(27)21-15-9-11-16(12-10-15)23(28)29/h1-3,5-6,9-12,17H,4,7-8,13H2,(H,21,27)(H,22,24)(H,25,26)/t17-/m0/s1

chave InChI

LFZGBNATHRHOKZ-KRWDZBQOSA-N

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Aplicação

N-Glutaryl-L-phenylalanine p-nitroanilide has been used as a substrate to determine chymotrypsin activity.

Ações bioquímicas/fisiológicas

N-Glutaryl-L-phenylalanine p-nitroanilide is useful in testing α-chymotrypsin activity.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Elsa Abuin et al.
Journal of colloid and interface science, 283(2), 539-543 (2005-02-22)
The rate of hydrolysis of N-glutaryl-L-phenylalanine p-nitroanilide (GPNA) catalyzed by alpha-chymotrypsin (alpha-CT) has been measured in aqueous solutions of dodecyltrimethylammonium bromide (DTAB) at concentrations below and above the critical micelle concentration, as well as in the absence of surfactant. Under
Elsa Abuin et al.
Journal of colloid and interface science, 308(2), 573-576 (2007-01-26)
The rate of N-glutaryl-L-phenylalanine p-nitroanilide hydrolysis catalyzed by alpha-chymotripsin has been measured in aqueous solutions of cetyltrimethylammonium bromide, tetradecyltrimethylammonium bromide, and dodecyltrimethylammonium bromide at concentrations below and above their critical micellar concentrations (CMC). For the three surfactants considered superactivity was
Takeshi Honda et al.
Chemical communications (Cambridge, England), (40)(40), 5062-5064 (2005-10-13)
A novel and facile method for the preparation of an enzyme-immobilized microreactor has been developed in which enzymes are immobilized as an enzyme-polymer membrane formed on the inner wall of the microchannel by a cross-linking polymerization method; the resulting microreactor
Anca Dragulescu-Andrasi et al.
Chemical communications (Cambridge, England), (2)(2), 244-246 (2005-02-23)
Guanidine-based peptide nucleic acid (GPNA) with a d-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.
Occurrence and identity of proteolytic bacteria in adult periodontitis.
D Grenier et al.
Journal of periodontal research, 29(5), 365-370 (1994-09-01)
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