Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

G2299

SAFC

L-Glutationa oxidada

Fabricação farmacêutica

Sinônimo(s):

GSSG, Glutatiol

Faça loginpara ver os preços organizacionais e de contrato

Selecione um tamanho

100 G
R$ 6.742,00
1 KG
R$ 44.443,00

R$ 6.742,00


Check Cart for Availability

Solicite uma grande encomenda

Selecione um tamanho

Alterar visualização
100 G
R$ 6.742,00
1 KG
R$ 44.443,00

About This Item

Fórmula empírica (Notação de Hill):
C20H32N6O12S2
Número CAS:
Peso molecular:
612.63
Beilstein:
1718700
Número CE:
Número MDL:
Código UNSPSC:
12352209
NACRES:
NA.21

R$ 6.742,00


Check Cart for Availability

Solicite uma grande encomenda

fonte biológica

synthetic

Nível de qualidade

Formulário

powder

solubilidade

H2O: 10 mg/mL, clear, colorless

adequação

suitable for manufacturing use

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

chave InChI

YPZRWBKMTBYPTK-BJDJZHNGSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Amino Acid Sequence

Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]

Descrição geral

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Informações legais

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

produto relacionado

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Kun-Peng Wang et al.
Molecular medicine reports, 9(5), 1813-1819 (2014-03-08)
Schisandra chinensis is a well-known traditional medicinal herb. Acetaminophen is a commonly used over-the-counter analgesic and overdose of acetaminophen was the most frequent cause of acute liver failure. However, no studies have demonstrated the role of Schisandra chinensis in acetaminophen-induced
Fabio Di Domenico et al.
Expert review of neurotherapeutics, 15(1), 19-40 (2014-09-23)
Alzheimer's disease (AD), characterized by progressive loss of memory, language, reasoning and other cognitive functions, including dementia, is characterized pathologically by the presence of senile plaques, neurofibrillary tangles and synapse loss. Increased oxidative/nitrosative stress, decreased antioxidants, mitochondrial damage and other
Vladimir L Kolossov et al.
Experimental biology and medicine (Maywood, N.J.), 239(4), 394-403 (2014-03-04)
The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, the underlying mechanisms behind this relationship are
Benoît Tessoulin et al.
Blood, 124(10), 1626-1636 (2014-07-10)
The aim of this study was to assess the efficiency of p53 reactivation and induction of massive apoptosis (PRIMA-1(Met)) in inducing myeloma cell death, using 27 human myeloma cell lines (HMCLs) and 23 primary samples. Measuring the lethal dose (LD50)
N Mohell et al.
Cell death & disease, 6, e1794-e1794 (2015-06-19)
Two main causes of platinum resistance are mutation in the tumor suppressor gene TP53 and drug-induced increase in intracellular glutathione concentration. Mutations in TP53 occur in about 50% of human tumors. APR-246 (PRIMA-1(MET)) is the first clinical-stage compound that reactivates

Questions

Reviews

No rating value

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica