F8307

FR-900098 monosodium salt

≥97% (NMR)

• Sinônimo(s): (3-(Acetylhydroxyamino)propyl)-phosphonic acid, BRN 2096083, P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid
• Fórmula empírica (Notação de Hill): C₅H₁₁NNaO₅P
• Número CAS: 73226-73-0
• Peso molecular: 219.11
• Número MDL: MFCD17215926
• Código UNSPSC: 51111800
• ID de substância PubChem: 329799770
• NACRES: NA.77

Propriedades

• Ensaio: ≥97% (NMR)
• forma: powder
• condição de armazenamento: desiccated; protect from light
• cor: white to light brown
• solubilidade: H₂O: ≥20 mg/mL
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na+].CC(=O)N(O)CCCP(O)([O-])=O
• InChI: 1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1
• chave InChI: LCFXFDGYDKNWMD-UHFFFAOYSA-M

Descrição

Ações bioquímicas/fisiológicas

1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable