E7879

β-Estradiol 17-acetate

≥99%

• Sinônimo(s): 1,3,5(10)-Estratriene-3,17β-diol 17-acetate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-acetate
• Fórmula empírica (Notação de Hill): C₂₀H₂₆O₃
• Número CAS: 1743-60-8
• Peso molecular: 314.42
• Beilstein: 2625732
• Número MDL: MFCD00056537
• Código UNSPSC: 12352200
• ID de substância PubChem: 24894658
• NACRES: NA.77

Propriedades

• esterilidade: non-sterile
• Ensaio: ≥99%
• forma: powder
• solubilidade: chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow
• Condições de expedição: ambient
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C
• InChI: 1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1
• chave InChI: QAHOQNJVHDHYRN-SLHNCBLASA-N

Descrição

Aplicação

β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.

Ações bioquímicas/fisiológicas

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

Características e benefícios

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Informações de segurança

• Pictogramas: GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H360FD,H410
• Declarações de precaução: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Classificações de perigo: Aquatic Chronic 1 - Repr. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Equipamento de proteção individual: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges