C6143

Chlorhexidine diacetate salt hydrate

bis(biguanide) antimicrobial

• Sinônimo(s): 1,6-Bis(N⁵-[p-chlorophenyl]-N¹-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
• Fórmula empírica (Notação de Hill): C₂₂H₃₀Cl₂N₁₀ · 2C₂H₄O₂ · xH₂O
• Número CAS: 206986-79-0
• Peso molecular: 625.55 (anhydrous basis)
• Número CE: 200-302-4
• Número MDL: MFCD00012532
• Código UNSPSC: 51102829
• ID de substância PubChem: 24892838
• NACRES: NA.85

Propriedades

• Formulário: powder
• CMC: 0.01% (25°C)(w/v)
• solubilidade: ethanol: 50 mg/mL
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria
• Modo de ação: cell membrane | interferes
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: ClC1=CC=C(NC(NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N)=N)C=C1.OC(C)=O.OC(C)=O
• InChI: 1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)
• chave InChI: WDRFFJWBUDTUCA-UHFFFAOYSA-N

Descrição

Aplicação

Used to study mechanism of membrane dysruption by bis(biguanide) molecules.

Ações bioquímicas/fisiológicas

Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective against both Gram-positive and Gram-negative bacteria. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Exoneração de responsabilidade

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Informações de segurança

• Pictogramas: GHS08,GHS07,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H302,H315,H319,H371,H410
• Declarações de precaução: P260 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P311
• Classificações de perigo: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2
• Órgãos-alvo: Liver,Teeth
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)