C4650
Cholestyramine resin
Sinônimo(s):
Colestyramine, Dowex 1X2 Cl--Form
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25 G
R$ 1.403,00
100 G
R$ 3.470,00
250 G
R$ 6.924,00
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25 G
R$ 1.403,00
100 G
R$ 3.470,00
250 G
R$ 6.924,00
About This Item
Produtos recomendados
Formulário
powder
Nível de qualidade
técnica(s)
activity assay: suitable
Matriz
polystyrene/divinylbenzene
pH
4—6
capacidade
~1.0 meq/g(dry)
Categorias relacionadas
Aplicação
Cholestyramine resin has been used:
- as a diet supplement to study the bile acid pool size and fecal bile acid output in mice
- to alter the bile acid (BA) levels and study its effect on liver fibrosis development in wild type (WT), fibroblast growth factor 15 (Fgf15)−/−, and Fgf15 transgenic (TG) mice
- in in vitro digestion process to study the capacity of the fractions for binding bile acid (BA)
Cholestyramine resin is used in protein chromatography, ion exchange chromatography and anion exchange media. Cholestyramine has been used to study the relief of postcholecystectomy diarrhea, the management of intractable cholestatic pruritus and obesity.
Ações bioquímicas/fisiológicas
Cholestyramine is a cationic exchange resin polymer. This resin is a bile acid sequestrant that interchanges chloride anions for bile acids of the small intestine lumen, leading to excretion of bile acids in the feces and reduced levels of serum bile acid. Cholestyramine is used to treat primary hypercholesterolemia. The resin induces dose-dependent reduction of low-density lipid (LDL) cholesterol. It ameliorates the risk of coronary artery disease.
Outras notas
Quartenary ammonium functional groups attached to cross-linked polystyrene
Informações legais
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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