C3788

Chondroitin sulfate B sodium salt

from Porcine intestinal mucosa, ≥90%, lyophilized powder

• Sinônimo(s): β-Heparin, Dermatan sulfate sodium salt
• Número CAS: 54328-33-5
• Número MDL: MFCD00151683
• Código UNSPSC: 12352201
• NACRES: NA.25

Propriedades

• fonte biológica: Porcine intestinal mucosa
• Nível de qualidade: 200
• Ensaio: ≥90%
• Formulário: lyophilized powder
• Impurezas: ≤20% water (Karl Fischer)
• cor: white
• solubilidade: H₂O: 5 mg/mL, clear, colorless
• traços de cátion: Na: 7.0-11.5%
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity.

Aplicação

Chondroitin sulfate B may be used to study its roles as a biomolecule receptor, mediator of cell signaling and cell binding molecule. It may be used to compare its properties to those of chondroitin sulfate A and chondroitin sulfate C. Chondroitin sulfate B is used to study β peptide(1-42) cytotoxicity.

Ações bioquímicas/fisiológicas

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.

Componentes

Chondroitin Sulfate B is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, L-iduronic acid, and sulfate residues in equimolar quantities where carbon 4 of the N-acetylgalactosamines is sulfated.

Atenção

Store this product at 2-8°C.

Nota de preparo

This product is soluble in water at 100 mg/mL.

Outras notas

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)