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Documentos Principais

C3050

Sigma-Aldrich

Cephalothin sodium salt

BioReagent, suitable for cell culture

Sinônimo(s):

7-(2-Thienylacetamido)cephalosporanic acid sodium salt, Cephalotin sodium salt

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About This Item

Fórmula empírica (Notação de Hill):
C16H15N2NaO6S2
Número CAS:
Peso molecular:
418.42
Beilstein:
4120706
Número CE:
Número MDL:
Código UNSPSC:
51101500
ID de substância PubChem:

linha de produto

BioReagent

Formulário

powder

técnica(s)

cell culture | mammalian: suitable

solubilidade

water: 50 mg/mL, clear, colorless to light yellow

espectro de atividade do antibiótico

Gram-positive bacteria

Modo de ação

cell wall synthesis | interferes

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C([O-])=O

InChI

1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1

chave InChI

VUFGUVLLDPOSBC-XRZFDKQNSA-M

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Descrição geral

Cephalotin is a first generation cephalosporin antibiotic.
Chemical structure: ß-lactam

Ações bioquímicas/fisiológicas

Mode of Action: Inhibits cell wall synthesis.
Antimicrobial spectrum: Gram-positive cocci.
Mode of Resistance: Cephalosporinase production.
Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.

Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.

Mode of Resistance: Production of cephalosporinase will inactivate the product.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Resp. Sens. 1 - Skin Sens. 1

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Visite a Biblioteca de Documentos

Jung-Whan Chon et al.
Journal of food science, 77(7), M354-M358 (2012-06-08)
A total of 115 desiccated food samples, including agricultural and marine products, were investigated for the presence of Cronobacter. Cronobacter species were characterized with biochemical tests. Antibiotic resistance was assessed with the disk diffusion method, and the molecular subtypes of
Sarah M Drawz et al.
Biochemistry, 49(2), 329-340 (2009-11-21)
The need to develop beta-lactamase inhibitors against class C cephalosporinases of Gram-negative pathogens represents an urgent clinical priority. To respond to this challenge, five boronic acid derivatives, including a new cefoperazone analogue, were synthesized and tested against the class C
Angela Gomes de Vasconcellos et al.
Japanese journal of infectious diseases, 65(1), 7-12 (2012-01-26)
Cellulitis is an important cause of hospitalization in pediatrics. Because Staphylococcus aureus is the main pathogen of cellulitis, medicinal therapeutics should take the changing resistance profile of this organism into consideration. The aim of this study was to evaluate the
Bulent Tokgoz et al.
Renal failure, 32(2), 179-184 (2010-03-05)
Aminoglycosides have been used in the treatment of CAPD peritonitis despite their potential risk for ototoxicity. The ototoxicity risk of intraperitoneally administered aminoglycosides has been investigated by a number of studies. However, their results are somewhat conflicting. The aim of
Reply: Protective effect of topical antibiotics in breast augmentation.
Philip K Pfeiffer et al.
Plastic and reconstructive surgery, 131(1), 115e-115e (2012-12-29)

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