C2901

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

≥95% (HPLC), powder

• Sinônimo(s): CCK-8, non-sulfated
• Fórmula empírica (Notação de Hill): C₄₉H₆₂N₁₀O₁₃S₂
• Número CAS: 25679-24-7
• Peso molecular: 1063.21
• Número MDL: MFCD00076488
• Código UNSPSC: 12352202
• ID de substância PubChem: 24892546
• NACRES: NA.32

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥95% (HPLC)
• Formulário: powder
• nº de adesão UniProt: P06307
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CSCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(Cc4ccccc4)C(N)=O
• InChI: 1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)
• chave InChI: OIXQINQYMGNCII-UHFFFAOYSA-N
• Informações sobre genes: human ... CCK(885)

Descrição

Amino Acid Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

Aplicação

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.[1]

Ações bioquímicas/fisiológicas

Biologically inactive form of CCK-8; CCK_B/gastrin receptor agonist that has no activity at the CCK_A receptor.

Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form.[2] CCK is mapped to human chromosome 3p22.1.[3] CCK interacts with receptors of the gastrointestinal tract and nervous system.[4] Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease.[5] CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).[6]

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)