B5438

Balsalazide disodium salt hydrate

• Sinônimo(s): 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
• Fórmula empírica (Notação de Hill): C₁₇H₁₃N₃Na₂O₆ · xH₂O
• Número CAS: 213594-60-6
• Peso molecular: 401.28 (anhydrous basis)
• Número MDL: MFCD18632541
• Código UNSPSC: 12352100
• ID de substância PubChem: 329773261
• NACRES: NA.25

Propriedades

• Ensaio: ≥99% (HPLC)
• forma: powder
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
• InChI: 1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
• chave InChI: ZZZXQZHSFPVNCR-HVARVCSCSA-L

Descrição

Ações bioquímicas/fisiológicas

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable