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B2629

Sigma-Aldrich

Betaine

≥98% (perchloric acid titration)

Sinônimo(s):

(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

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About This Item

Fórmula linear:
(CH3)3N+CH2COO-
Número CAS:
107-43-7
Peso molecular:
117.15
Beilstein:
3537113
Número CE:
203-490-6
Número MDL:
MFCD00012123
Código UNSPSC:
12352202
ID de substância PubChem:
24891663
NACRES:
NA.77

fonte biológica

sugar beets

Nível de qualidade

200

Ensaio

≥98% (perchloric acid titration)

forma

powder or crystals

pf

310 °C (dec.)

solubilidade

water: 50 mg/mL, clear, colorless to faintly yellow

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3

chave InChI

KWIUHFFTVRNATP-UHFFFAOYSA-N

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Descrição geral

Betaine is a quaternary ammonium zwitterion, extensively present in animals, plants and microorganisms. It also forms a good dietary source as it is found in wheat, spinach, shellfish and sugar beets. Betaine is a methyl derivative of the amino acid glycine. It is known by different names such as trimethylglycine, glycine betaine, lycine and oxyneurine.

Aplicação

Betaine has been used to study the effects of antioxidants on regrowth from cryopreservation.

Ações bioquímicas/fisiológicas

Apart from betaine taking part in transmethylation, it acts as an organic osmolyte in protecting cells under stress. This is being significantly observed in plants and microorganisms. Betaine is also known to increase the levels of S-adenosylmethionine and thus this might reduce the effects of hepatic steatosis.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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N-(3-Sulfopropyl)-N-methacroyloxyethyl- N,N-dimethylammonium betaine for synthesis

Sigma-Aldrich

8.18484

N-(3-Sulfopropyl)-N-methacroyloxyethyl- N,N-dimethylammonium betaine

Cloreto de colina ≥99%

Sigma-Aldrich

C7017

Cloreto de colina

L Garcia-Gonzalez et al.
International journal of food microbiology, 129(3), 253-263 (2009-01-23)
High pressure carbon dioxide (HPCD) treatment is currently considered as an attractive non-thermal process for preserving food. Industrial application of this technique requires, among others, systematic (quantitative) data on the inactivation of food relevant pathogenic and spoilage microorganisms, and in-depth
Antioxidant and anti-stress compounds improve regrowth of cryopreserved Rubus shoot tips
Uchendu EE, et al.
In Vitro Cellular & Developmental Biology, 46(4), 386-393 (2010)
Jindong Hao et al.
Animals : an open access journal from MDPI, 11(6) (2021-07-03)
m6A is one of the most common and abundant modifications of RNA molecules present in eukaryotes. The methyltransferase complex, consisting of methyltransferase-like 3 (METTL3), METTL14, and WTAP, is responsible for the m6A modification of RNA. WTAP was identified as an
Yuna Choi et al.
Experimental neurobiology, 30(4), 308-317 (2021-09-07)
Experimental autoimmune uveitis (EAU) is an animal model of human autoimmune uveitis that is characterized by the infiltration of autoimmune T cells with concurrent increases in pro-inflammatory cytokines and reactive oxygen species. This study aimed to assess whether betaine regulates
Lei Gao et al.
International journal of molecular sciences, 22(14) (2021-07-25)
The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily permeable and able to protect MSCs from cryo-injuries
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