C7017

Cloreto de colina

≥99%

• Sinônimo(s): Cloreto de (2-hidroxietil)trimetilamônio
• Fórmula linear: (CH₃)₃N(Cl)CH₂CH₂OH
• Número CAS: 67-48-1
• Peso molecular: 139.62
• Beilstein: 3563126
• Número CE: 200-655-4
• Número MDL: MFCD00011721
• Código UNSPSC: 50501514
• ID de substância PubChem: 57654039
• NACRES: NA.25

Propriedades

• fonte biológica: synthetic
• Ensaio: ≥99%
• forma: powder
• cor: white
• pf: 302-305 °C (dec.) (lit.)
• tipo de lipídio: phospholipids
• cadeia de caracteres SMILES: [Cl-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
• chave InChI: SGMZJAMFUVOLNK-UHFFFAOYSA-M

Descrição

Descrição geral

Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.

Aplicação

Choline chloride has been used:

• in choline release assay
• as an endogenous agonist of sigma-1 receptors (Sig-1Rs)
• as a standard to analyse interrelationships between methionine and choline metabolism

Ações bioquímicas/fisiológicas

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Substratos

Substrato de colina acetiltransferase

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves