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A9736

Sigma-Aldrich

A-438079 hydrochloride hydrate

≥98% (HPLC)

Sinônimo(s):

3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate

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About This Item

Fórmula empírica (Notação de Hill):
C13H9Cl2N5·HCl · xH2O
Número CAS:
899431-18-6
Peso molecular:
342.61 (anhydrous basis)
Número MDL:
MFCD17215929
Código UNSPSC:
12352200
ID de substância PubChem:
329771058
NACRES:
NA.77

Nível de qualidade

100

Ensaio

≥98% (HPLC)

forma

powder

condição de armazenamento

desiccated

cor

white to beige

solubilidade

DMSO: 20 mg/mL, clear

originador

Abbott

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3

InChI

1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2

chave InChI

ZHFJJBAKSROKNO-UHFFFAOYSA-N

Aplicação

A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.

Ações bioquímicas/fisiológicas

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

Características e benefícios

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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