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A0263

Sigma-Aldrich

Aflatoxin G2

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About This Item

Fórmula empírica (Notação de Hill):
C17H14O7
Número CAS:
Peso molecular:
330.29
Beilstein:
1692017
Número CE:
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77
Preço e disponibilidade não estão disponíveis no momento.

Formulário

powder

Nível de qualidade

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H][C@@]12CCO[C@]1([H])Oc3cc(OC)c4C5=C(C(=O)OCC5)C(=O)Oc4c23

InChI

1S/C17H14O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h6,8,17H,2-5H2,1H3/t8-,17+/m0/s1

chave InChI

WPCVRWVBBXIRMA-WNWIJWBNSA-N

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Descrição geral

Aflatoxin G2 is a fungal secondary toxic metabolite synthesized by Aspergillus parasiticus, Aspergillus flavus, and Aspergillus nomius,[1] species that are found in tropical and subtropical regions of the world.[2] Aflatoxin Gs (AFGs) are derivatives of difuranocoumarin and contain a bifuran group linked to a coumarin nucleus and a lactone ring.[3]

Aplicação

Aflatoxin G2 has been used as a standard to estimate the levels of aflatoxins by immunoaffinity column cleanup in:
  • peanut confection[4]
  • Ginseng and other roots[5]
  • olive oil, peanut oil, and sesame oil[6]

Ações bioquímicas/fisiológicas

Aflatoxins are hepatocarcinogenic and act as food contaminants in peanuts, fruits, cereals, corn, and dry fruits.[1]

Advertência

Possibly carcinogenic.

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Carc. 1B - Muta. 1B

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Dipendra K Mahato et al.
Frontiers in microbiology, 10, 2266-2266 (2019-10-23)
Aflatoxins produced by the Aspergillus species are highly toxic, carcinogenic, and cause severe contamination to food sources, leading to serious health consequences. Contaminations by aflatoxins have been reported in food and feed, such as groundnuts, millet, sesame seeds, maize, wheat
Meritxell Ventura et al.
Journal of chromatography. A, 1048(1), 25-29 (2004-09-30)
An easy method for the determination of aflatoxins B1, G1, B2 and G2 in Rhammus purshiana by LC coupled to mass spectrometry has been developed. Aflatoxins were extracted with a mixture of methanol and water and then it was purified
Evaluation and improvement of extraction methods for the analysis of aflatoxins B1, B2, G1 and G2 from naturally contaminated maize
Bertuzzi T, et al.
Food Analytical Methods, 512-519 (2012)
Maria Helena Iha et al.
Journal of chromatography. A, 1483, 1-7 (2017-01-09)
The aim of this study was to investigate the feasibility of using multitime-regenerated immunoaffinity column (IAC) for aflatoxins B1, B2, G1 and G2 in peanut confection. After each use, the IAC was washed immediately with phosphate-buffered saline and stored for >12h
Mary Trucksess et al.
Journal of AOAC International, 89(3), 624-630 (2006-06-24)
Mycotoxins are toxic secondary metabolites produced by certain molds and are common contaminants of many important food crops, such as grains, nuts, and spices. Some mycotoxins are found in fruits, vegetables, and botanical roots. These contaminants have a broad range

Artigos

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Questions

  1. Can Aflatoxin G2 A0263 be used for analysis with HPLC?

    1 answer
    1. Aflatoxin G2 A0263 has not been validated for HPLC analysis. A relevant citation for the product's use in HPLC analysis is available for reference: J AOAC Int. 2010 May-Jun;93(3):936-42.

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