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75068

Sigma-Aldrich

9,10-Anthracenediyl-bis(methylene)dimalonic acid

BioReagent, suitable for fluorescence, ≥90% (HPCE)

Sinônimo(s):

ABDA, Single Oxygen Probe

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50 MG
R$ 1.159,00

R$ 1.159,00


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50 MG
R$ 1.159,00

About This Item

Fórmula empírica (Notação de Hill):
C22H18O8
Número CAS:
Peso molecular:
410.37
Beilstein:
3503804
Número MDL:
Código UNSPSC:
12352106
ID de substância PubChem:
NACRES:
NA.32

R$ 1.159,00


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linha de produto

BioReagent

Nível de qualidade

Ensaio

≥90% (HPCE)

Formulário

powder

solubilidade

DMSO: soluble

fluorescência

λex 380 nm; λem 407 nm in 0.1 M phosphate pH 7.0

adequação

suitable for fluorescence

cadeia de caracteres SMILES

OC(=O)C(Cc1c2ccccc2c(CC(C(O)=O)C(O)=O)c3ccccc13)C(O)=O

InChI

1S/C22H18O8/c23-19(24)17(20(25)26)9-15-11-5-1-2-6-12(11)16(10-18(21(27)28)22(29)30)14-8-4-3-7-13(14)15/h1-8,17-18H,9-10H2,(H,23,24)(H,25,26)(H,27,28)(H,29,30)

chave InChI

DNUYOWCKBJFOGS-UHFFFAOYSA-N

Descrição geral

9,10-Anthracenediyl-bis(methylene)dimalonic acid or ABDA is a singlet oxygen probe.[1] It is highly fluorescent and soluble in water and binds to lipopolysaccharides (LPS) found in the cell membrane. 9,10-Anthracenediyl-bis(methylene)dimalonic acid takes four negative charges upon fully deprotonation in neutral aqueous solutions, stabilizing the ion-pair complex and facilitating selective recognition of LPS over other common ionic species of clinical significance. In addition to the emission maximum at 407 nm, there are lower maxima at 431, 457, and 485 nm.

Aplicação

9,10-Anthracenediyl-bis(methylene)dimalonic acid is widely used as a singlet oxygen detector probe. [1] 9,10-Anthracenediyl-bis(methylene)dimalonic acid is suitable for assessing the photodynamic effect of curcumin Vibrio parahaemolyticus, which is a significant cause of bacterial diarrhea.[2]

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota de análise

In addition to the emission maximum at 407 nm, there are lower maxima at 431, 457 and 485 nm.

Outras notas

Reagent for the assay of singlett oxygen; it has better characteristics than 9,10-anthracenediyl-bis-dipropionic acid[3]

Pictogramas

Exclamation markEnvironment

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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Vladimíra Pavlíčková et al.
Molecules (Basel, Switzerland), 24(24) (2019-12-11)
Purpurin 18 derivatives with a polyethylene glycol (PEG) linker were synthesized as novel photosensitizers (PSs) with the goal of using them in photodynamic therapy (PDT) for cancer. These compounds, derived from a second-generation PS, exhibit absorption at long wavelengths; considerable
Saya Otake et al.
Bioconjugate chemistry, 29(6), 2068-2073 (2018-05-16)
FLNBD-BAMPEG2k, bearing a nitrobenzoxadiazole (NBD) unit and an oleyl terminus conjugated via a poly(ethylene glycol) (PEG) spacer ( Mn = 2,000), was designed to fluorescently label cell membranes by docking its hydrophobic oleyl terminus. During laser scanning microscopy in a
Roxana Jijie et al.
Colloids and surfaces. B, Biointerfaces, 170, 347-354 (2018-06-26)
In the last years, carbon-based nanomaterials have attracted considerable attention in a wide range of fields, particularly in biomedicine, owing to their remarkable photo-physical and chemical properties. In this study, we demonstrate that amine-terminated carbon dots (CDs-NH2) functionalized with ampicillin
Juan Wu et al.
Photodiagnosis and photodynamic therapy, 15, 34-39 (2016-05-15)
Vibrio parahaemolyticus (V. parahaemolyticus) is currently a major cause of bacterial diarrhoea associated with seafood consumption. The objective of this study was to determine the inactivation effect of curcumin-mediated photodynamic action on V. parahaemolyticus. First of all, V. parahaemolyticus suspended
Takehiro Yumoto et al.
Organic & biomolecular chemistry, 18(34), 6702-6709 (2020-08-22)
Porphyrin derivatives with hydroxyphenyl or dihydroxyphenyl moieties in the meso-position were able to dissolve in water by complexation with two trimethyl-β-cyclodextrins (TMe-β-CDxs) without further chemical modification of porphyrins or addition of dimethyl sulfoxide as a co-solvent. TMe-β-CDx-complexed tetra(hydroxyphenyl)porphyrins (THPPs) with

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