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74480

Sigma-Aldrich

L-Norepinephrine hydrochloride

≥98.0% (sum of enantiomers, HPLC)

Sinônimo(s):

L-Arterenol hydrochloride, L-Noradrenaline hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C8H11NO3 · HCl
Número CAS:
329-56-6
Peso molecular:
205.64
Beilstein:
3916100
Número CE:
206-345-5
Número MDL:
MFCD00064560
Código UNSPSC:
12352209
ID de substância PubChem:
57652452
NACRES:
NA.77

Ensaio

≥98.0% (sum of enantiomers, HPLC)

forma

crystals

atividade óptica

[α]20/D −38.5±5°, c = 2% in H2O

pf

~150 °C (dec.)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl[H].NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H/t8-;/m0./s1

chave InChI

FQTFHMSZCSUVEU-QRPNPIFTSA-N

Informações sobre genes

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

Categorias relacionadas

Ações bioquímicas/fisiológicas

Adrenal medullary stress hormone, mediator of the fight-or-flight response; and the primary neurotransmitter in the post-ganglionic sympathetic (adrenergic) nervous system.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H300 + H310 + H330

Classificações de perigo

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Dopamina

Sigma-Aldrich

H8502

Dopamina

(−)-Epinephrine

Sigma-Aldrich

E4250

(−)-Epinephrine

Molibdato de amônio ACS reagent, 99.98% trace metals basis

Sigma-Aldrich

431346

Molibdato de amônio

Adenosine 3′-phosphate 5′-phosphosulfate triethylammonium salt ≥90.0% (HPLC)

Sigma-Aldrich

94455

Adenosine 3′-phosphate 5′-phosphosulfate triethylammonium salt

Virginie Montiel et al.
Science translational medicine, 12(564) (2020-10-09)
Pathological remodeling of the myocardium has long been known to involve oxidant signaling, but strategies using systemic antioxidants have generally failed to prevent it. We sought to identify key regulators of oxidant-mediated cardiac hypertrophy amenable to targeted pharmacological therapy. Specific
Anyue Yin et al.
British journal of pharmacology, 175(16), 3394-3406 (2018-06-03)
Development of combination therapies has received significant interest in recent years. Previously, a two-receptor one-transducer (2R-1T) model was proposed to characterize drug interactions with two receptors that lead to the same phenotypic response through a common transducer pathway. We applied
Giovanni D'Andrea et al.
Scientific reports, 9(1), 6151-6151 (2019-04-18)
Early diagnosis of Parkinson's disease (PD) remains a challenge to date. New evidence highlights the potential clinical value of circulating trace amines (TAs) in early-stage PD and their involvement in disease progression. A new ultra performance chromatography mass spectrometry (UPLC-MS/MS)
Andrew S Terker et al.
Hypertension (Dallas, Tex. : 1979), 64(1), 178-184 (2014-05-07)
Excessive renal efferent sympathetic nerve activity contributes to hypertension in many circumstances. Although both hemodynamic and tubular effects likely participate, most evidence supports a major role for α-adrenergic receptors in mediating the direct epithelial stimulation of sodium retention. Recently, it
Wataru Inoue et al.
Nature neuroscience, 16(5), 605-612 (2013-04-09)
Exposure to a stressor sensitizes behavioral and hormonal responses to future stressors. Stress-associated release of noradrenaline enhances the capacity of central synapses to show plasticity (metaplasticity). We found noradrenaline-dependent metaplasticity at GABA synapses in the paraventricular nucleus of the hypothalamus
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