121R-1

CD21 (EP3093) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: EP3093, monoclonal
• descrição: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (121R-14); vial of 0.5 mL concentrate (121R-15); bottle of 1.0 mL predilute (121R-17); vial of 1.0 mL concentrate (121R-16); bottle of 7.0 mL predilute (121R-18)
• fabricante/nome comercial: Cell Marque^®
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• Isotipo: IgG
• controle: tonsil
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: membranous
• Informações sobre genes: human ... CR2(1380)

Descrição

Descrição geral

CD21 (also known as complement receptor 2 (CR2), C3d receptor, or EBV receptor) is a 140 kDa membrane protein on B-lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells.[1] The antigen is absent on T-lymphocytes, monocytes, and granulocytes.[2][3]
Anti-CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue. This antibody also labels follicular dendritic cell sarcomas.[2][4][5] Anti-CD21 is valuable in differentiating follicular lymphoma with marginal zone differentiation from marginal zone lymphoma with follicular involvement. It also plays a role in separating among nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte-rich classic Hodgkin lymphoma, and T-cell/histiocyte-rich B-cell lymphoma in combination with other B-cell and T-cell markers.[6]Anti-CD21 is also useful in identifying abnormal follicular dendritic cell pattern in angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma.[7]

Qualidade

IVD

IVD

IVD

RUO

Ligação

CD21 Positive Control Slides, Product No. 121S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

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Outras notas

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Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany