The specific epitope sequence is not available. This gene is mapped to human chromosome 11q23.2–11q23.3. The immunogen is a phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
SAB5600038
Anti-Gamma H2AX (phospho-Ser139) antibody, Rabbit monoclonal
recombinant, expressed in HEK 293 cells, clone RM224, purified immunoglobulin
Sinônimo(s):
H2AX Ser139 p, Histone H2AX (phospho ser139)
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100 μG
R$ 3.663,00
R$ 3.663,00
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100 μG
R$ 3.663,00
About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
R$ 3.663,00
Check Cart for Availability
Produtos recomendados
recombinante
expressed in HEK 293 cells
Nível de qualidade
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
RM224, monoclonal
recombinant monoclonal
Formulário
buffered aqueous glycerol solution
reatividade de espécies
human
concentração
~1 mg/mL
técnica(s)
ELISA: 0.2- 1 μg/mL
immunoblotting: 0.5-2 μg/mL
immunocytochemistry: 0.5-2 μg/mL
Isotipo
IgG
nº de adesão NCBI
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
phosphorylation (pSer139)
Informações sobre genes
human ... H2AX(3014)
Descrição geral
Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2–11q23.3.
Especificidade
This antibody reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
Imunogênio
Synthetic peptide corresponding to Phospho-Histone H2AX (Ser139)
Ações bioquímicas/fisiológicas
H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.
Características e benefícios
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forma física
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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