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Documentos

Y0001027

Betamethasone valerate for system suitability

Name: Betamethasone valerate for system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Betamethasone 17-valerate, 1,4-Pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17-valerate, 9α-Fluoro-16β-methylprednisolone 17-valerate, Betnovate

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About This Item

Fórmula empírica (Notação de Hill):

C₂₇H₃₇FO₆

Número CAS:

2152-44-5

Peso molecular:

476.58

Beilstein:

4240001

Número MDL:

MFCD00867446

Código UNSPSC:

41116107

ID de substância PubChem:

329831226

NACRES:

NA.24

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Y0001065

Betamethasone valerate impurity mixture

B1055000

Betamethasone 21-valerate

B1000000

Betamethasone

B1054000

Betamethasone 17-valerate

Supelco

PHR1921

Propionato de Clobetasol

Supelco

PHR1780

Betamethasone Valerate

BP089

Cloxacillin sodium

Y0001733

Permethrin (25:75)

BP043

Betamethasone 21-valerate

Y0002164

propionato de clobetasol

grau

pharmaceutical primary standard

família API

betamethasone

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CCCCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CO

InChI

1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19?,20?,21-,24-,25-,26-,27-/m0/s1

chave InChI

SNHRLVCMMWUAJD-QDHNOTTGSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Betamethasone valerate for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

Nº do produto

Descrição

Preços

Palavra indicadora

Danger

Frases de perigo

H360FD,H373

Declarações de precaução

P202 - P260 - P280 - P308 + P313 - P405 - P501

Classificações de perigo

Repr. 1B - STOT RE 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

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Certificados de análise (COA)

Lot/Batch Number

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Comparison of steroid antibiotic pack and 10% ichthammol glycerine pack in relieving pain of acute otitis externa in children.

Prakash Adhikari et al.

International journal of pediatric otorhinolaryngology, 75(4), 500-503 (2011-02-05)

This study was carried out with the objective of comparing clinical efficacy of 10% ichthammol glycerine (IG) pack with steroid-antibiotic pack for relieving pain in cases of acute otitis externa. A prospective quasi-randomized clinical trial was completely carried out in

Clinical and cytological effects of pimecrolimus cream 1% after resolution of active atopic dermatitis lesions by topical corticosteroids: a randomized controlled trial.

Christine Bangert et al.

Dermatology (Basel, Switzerland), 222(1), 36-48 (2010-12-15)

Topical pimecrolimus may maintain remissions of atopic dermatitis (AD) by inhibiting subclinical inflammation. To evaluate clinical and cytological effects of pimecrolimus in topical corticosteroid-treated and resolved AD lesions. Patients (n=67) with resolved AD lesions were randomized to 3-week double-blind treatment

Photodegradation and stabilization of betamethasone-17 valerate in aqueous/organic solvents and topical formulations.

Saif-ur-Rehman Khattak et al.

AAPS PharmSciTech, 14(1), 177-182 (2012-12-20)

The effects of solvent [acetonitrile, methanol, and acetonitrile/water mixture (20:80, v/v)], buffer concentration (phosphate buffer, pH 7.5), ionic strength and commonly employed adjuvants on the photodegradation of betamethasone-17 valerate in cream and gel formulations have been studied on exposure to UV

Differential suppression of epidermal antimicrobial protein expression in atopic dermatitis and in EFAD mice by pimecrolimus compared to corticosteroids.

Jens-Michael Jensen et al.

Experimental dermatology, 20(10), 783-788 (2011-06-29)

It has been suggested that the increased rate of bacterial infection in atopic dermatitis (AD) may be caused by reduced antimicrobial protein (AMP) expression. We were interested whether common treatments in AD affect antimicrobial defense. We investigated the effects of

Low-frequency ultrasound sonophoresis to increase the efficiency of topical steroids: a pilot randomized study of humans.

Annabel Maruani et al.

International journal of pharmaceutics, 395(1-2), 84-90 (2010-05-18)

Topical steroids are efficient in vasoconstriction potential, which is linked to their anti-inflammatory activity. Low-frequency ultrasound (US) applied on the skin (sonophoresis) may enhance the transdermal transport of various steroids. We aimed to assess, in a simple, blinded, randomized controlled

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