Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

T2695

Supelco

Tetrandrine

analytical standard, for drug analysis

Sinônimo(s):

(1β)-6,6′,7,12-Tetramethoxy-2,2′-dimethylberbaman

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula empírica (Notação de Hill):
C38H42N2O6
Número CAS:
518-34-3
Peso molecular:
622.75
Número MDL:
MFCD08689909
Código UNSPSC:
41116107
ID de substância PubChem:
329826723
NACRES:
NA.24

grau

analytical standard, for drug analysis

Nível de qualidade

100

Ensaio

≥90%

forma

solid

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

formato

neat

cadeia de caracteres SMILES

COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34

InChI

1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1

chave InChI

WVTKBKWTSCPRNU-KYJUHHDHSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

Tetrandrine (TET) is classified under the bisbenzylisoquinoline alkaloid family of compounds extracted from Stephania tetrandra S. Moore.

Aplicação

Analgesic, antipyretic.
TET may be used as an analytical reference standard for the determination of TET in:
  • Blood samples by online multidimensional solid phase extraction liquid chromatography coupled to tandem mass spectrometry (MD-SPE-LC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.
  • Rat plasma by ultra-high performance liquid chromatography (UHPLC) combined with MS/MS with MRM detection.
  • Qi-Fang-Xi-Bi-Granules used in Chinese medicine by reversed phase HPLC equipped with ultraviolet (UV) detector.
  • Fangji Huangqi Tang Chinese medicine by UHPLC coupled to triple quadrupole mass spectrometry (QqQ-MS) with MRM detection.

It may be used as an internal standard for the determination of hernandezine in:
  • Rat plasma and tissues by UHPLC-MS/MS with MRM detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H300

Declarações de precaução

P264 - P270 - P301 + P310 - P405 - P501

Classificações de perigo

Acute Tox. 2 Oral

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number
MKCS5461
MKCS5642
MKCP7839
MKCP7276
MKCJ4398

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 1

1 of 1

Berberine chloride form

Sigma-Aldrich

B3251

Berberine chloride form

C Y Kwan et al.
Life sciences, 68(7), 841-847 (2001-02-24)
The effects of tetrandrine (TET), a Ca2+ antagonist of bis-benzylisoquinoline alkaloid origin, on cultured single bovine pulmonary artery endothelial cells were examined using fluorescence ratio imaging and whole-cell attached patch-clamp techniques. Thapsigargin (TSG, 100 nM), a selective endoplasmic reticulum Ca2+-ATPase
Development and validation of an UHPLC-QqQ-MS technique for simultaneous determination of ten bioactive components in Fangji Huangqi Tang.
Wang X, et al.
Journal of Analytical Methods in Chemistry, 2016(8), 1328-1332 (2016)
Determination of a novel anticancer AMPK activator hernandezine in rat plasma and tissues with a validated UHPLC-MS/MS method: Application to pharmacokinetics and tissue distribution study.
Song Y, et al.
Journal of Pharmaceutical and Biomedical Analysis, 141(8), 132-139 (2017)
Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts.
Wang X, et al.
Journal of Separation Science, 38(8), 1286-1293 (2015)
Development and validation of an on-line multidimensional SPE-LC-MS/MS method for the quantitation of Tetrandrine in blood samples.
Caglar S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 988, 25-32 (2015)
Exibir todos os documentos relacionados

Artigos

NF-κB and Inflammation

Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica