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Documentos Principais

PHR1280

Supelco

Xylitol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Xylite

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About This Item

Fórmula linear:
HOCH2[CH(OH)]3CH2OH
Número CAS:
Peso molecular:
152.15
Beilstein:
1720523
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. X0080000
traceable to USP 1720600

família API

xylitol

Certificado de análise (CofA)

current certificate can be downloaded

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

94-97 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

OC[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+

chave InChI

HEBKCHPVOIAQTA-SCDXWVJYSA-N

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Descrição geral

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Xylitol is a naturally occurring polyhydric sugar alcohol with high sweetening power and anticariogenic properties.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Xylitol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by capillary isotachophoresis.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC4431 in the slot below. This is an example certificate only and may not be the lot that you receive.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

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Y0000177

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Isomalt Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

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Adonitol ≥99%

Sigma-Aldrich

A5502

Adonitol

Sugar Alcohol Kit (individually packaged in quantities indicated), analytical standard

Supelco

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Sugar Alcohol Kit

The effect of xylitol on dental caries and oral flora
Nayak PA, et al.
Clinical, cosmetic and investigational dentistry, 6, 89-89 (2014)
Separation and determination of sorbitol and xylitol in multi-component pharmaceutical formulations by capillary isotachophoresis
Pospisilova M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 17(3), 387-392 (1998)
Kiet A Ly et al.
Pediatric dentistry, 28(2), 154-163 (2006-05-20)
The purpose of this report was to provide an overview of xylitol and other polyol sweeteners and dental caries for clinicians and to discuss current applications for dental practice and potential community-based public health interventions. Xylitol, like other polyol sweeteners
Tom Birger Granström et al.
Applied microbiology and biotechnology, 74(2), 277-281 (2007-01-12)
The rare sugar xylitol is a five-carbon polyol (pentitol) that has beneficial health effects. Xylitol has global markets and, therefore, it represents an alternative to current dominant sweeteners. The research on microbial reduction of D-xylose to xylitol has been focused
Xiaoxiao Guo et al.
Bioresource technology, 128, 547-552 (2012-12-06)
In this study, an integrated xylitol production pathway, directly using xylan as the substrate, was constructed in Candida tropicalis BIT-Xol-1 which could efficiently convert xylose into xylitol. In order to consolidate this bioprocessing, a β-1,4-xylanase gene (atn) and a β-xylosidase

Protocolos

Separation of Maltotriose; Maltose; Xylitol

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