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Documentos Principais

PHR1019

Supelco

Álcool benzílico

Benzyl alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Benzeno-metanol

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1 G
R$ 573,00

R$ 573,00


Disponível para enviar em10 de abril de 2025Detalhes


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1 G
R$ 573,00

About This Item

Fórmula linear:
C6H5CH2OH
Número CAS:
Peso molecular:
108.14
Beilstein:
878307
Número CE:
Número MDL:
Código UNSPSC:
12352104
eCl@ss:
39023110
ID de substância PubChem:
NACRES:
NA.24

R$ 573,00


Disponível para enviar em10 de abril de 2025Detalhes


Solicite uma grande encomenda

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. Y0000167
traceable to USP 1061901

densidade de vapor

3.7 (vs air)

pressão de vapor

13.3 mmHg ( 100 °C)
3.75 mmHg ( 77 °C)

família API

benzalkonium chloride

Certificado de análise (CofA)

current certificate can be downloaded

temperatura de autoignição

817 °F

prazo de validade

~3 yr

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

índice de refração

n20/D 1.539 (lit.)

p.e.

203-205 °C (lit.)

pf

−16-−13 °C (lit.)

densidade

1.045 g/mL at 25 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

OCc1ccccc1

InChI

1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2

chave InChI

WVDDGKGOMKODPV-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzyl alcohol is used as a preservative in pharmaceutical preparations in concentration up to 2% and as a solubilizer in concentrations of 5%. It is effective against gram-positive organisms.[1]

Aplicação

Benzyl alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography[2] and spectrophotometry.[3][4]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC1678 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

213.8 °F - DIN 51758

Ponto de fulgor (°C)

101 °C - DIN 51758


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Certificados de análise (COA)

Lot/Batch Number

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Full spectrum and selected spectrum based multivariate calibration methods for simultaneous determination of betamethasone dipropionate, clotrimazole and benzyl alcohol: Development, validation and application on commercial dosage form.
Darwish HW, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 169, 50-57 (2016)
Simultaneous determination of bifonazole and benzyl alcohol in pharmaceutical formulations by reverse-phase HPLC.
Cudina OA, et al.
Chromatographia, 61(7-8), 415-418 (2005)
Simultaneous spectrophotometric determination of benzyl alcohol and diclofenac in pharmaceuticals using methods based on the first derivative of the optical density ratio.
Ghasemi J, et al.
Pharmaceutical Chemistry Journal, 39(12) (2005)
Simultaneous spectrophotometric determination of piroxicam and benzyl alcohol in gel forms.
Goger NG, et al.
Chem. Anal. (Warsaw), 50(6), 1059-1059 (2005)
Béatrice Hechler et al.
The Journal of pharmacology and experimental therapeutics, 314(1), 232-243 (2005-03-29)
Our aim was to determine whether the newly described P2X1 antagonist NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt] could selectively antagonize the platelet P2X1 receptor and how it affected platelet function. NF449 inhibited alpha,beta-methyleneadenosine 5'-triphosphate-induced shape change (IC50 = 83 +/- 13

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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