C4786

Cefoxitin sodium salt

• Fórmula empírica (Notação de Hill): C₁₆H₁₆N₃NaO₇S₂
• Número CAS: 33564-30-6
• Peso molecular: 449.43
• Número CE: 251-574-6
• Número MDL: MFCD00079042
• Código UNSPSC: 41116107
• ID de substância PubChem: 329775070
• NACRES: NA.24

Propriedades

• forma: powder or granules
• Nível de qualidade: 200
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): forensics and toxicology; pharmaceutical (small molecule); veterinary
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [Na+].CO[C@]2(NC(=O)Cc1cccs1)C3SCC(COC(N)=O)=C(N3C2=O)C([O-])=O
• InChI: 1S/C16H17N3O7S2.Na/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19;/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22);/q;+1/p-1/t14-,16+;/m1./s1
• chave InChI: GNWUOVJNSFPWDD-XMZRARIVSA-M

Descrição

Descrição geral

Cefoxitin is a β-lactam that belongs to the group of cephamycin antibiotics and is considered a 2^nd generation cephalosporin. It shows resistance to β-lactamases and is used to treat a broad spectrum of bacterial infections caused by gram-positive and gram-negative bacteria, such as bronchitis, pharyngitis, meningitis, and urinary tract infection among others. It is used for intravenous and intramuscular injections. It is found to be active against Bacteroides and is therapeutically used for the treatment of mixed aerobic-anaerobic infections.

Aplicação

The analytical standard can be used to:

• Determine cefoxitin sodium using four stability-indicating spectrophotometric methods in the presence of its alkaline degradation products in its pure form and pharmaceutical dosage forms
• Separate and measure cefoxitin sodium in commercial drug products by high-performance liquid chromatography (HPLC)

Outras notas

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1B
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves