939048

Lithium bis(trimethylsilyl)amide ChemBeads

• Sinônimo(s): Hexamethyldisilazane lithium salt ChemBeads
• Fórmula empírica (Notação de Hill): LiC₆H₁₈NSi₂
• Peso molecular: 167.33
• Número MDL: MFCD00008261
• Código UNSPSC: 12352100

Propriedades

• descrição: Organic Salt
• Nível de qualidade: 100
• Formulário: solid
• composição: 14-16 wt% loading of base
• adequação da reação: core: lithium
• cadeia de caracteres SMILES: [Li]N([Si](C)(C)C)[Si](C)(C)C
• InChI: 1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• chave InChI: YNESATAKKCNGOF-UHFFFAOYSA-N

Descrição

Descrição geral

Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.

Aplicação

Base employed in generating enolates for the preparation of lactone precursors, pyranones, and cyclohexanes. Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.[6] Also used in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. For general uses, product is also available in powdered form (324620)

Características e benefícios

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Outras notas

• High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads
• Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughout Experimentation
• ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Informações de segurança

• Pictogramas: GHS02,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H228,H251,H314
• Declarações de precaução: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• Perigos de suplementos: EUH014
• Código de classe de armazenamento: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 62.6 °F - closed cup
• Ponto de fulgor (°C): 17 °C - closed cup