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Documentos Principais

91827

Supelco

Biotina

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Sinônimo(s):

D-Biotina, Bios II, Coenzima R, Vitamina B7, Vitamina H

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About This Item

Fórmula empírica (Notação de Hill):
C10H16N2O3S
Número CAS:
Peso molecular:
244.31
Beilstein:
86838
Número CE:
Número MDL:
Código UNSPSC:
41116107
eCl@ss:
34058011
ID de substância PubChem:
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

certified reference material
TraceCERT®

Nível de qualidade

linha de produto

TraceCERT®

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

técnica(s)

HPLC: suitable
LC/MS: suitable
gas chromatography (GC): suitable

cor

white

pf

231-233 °C (lit.)

aplicação(ões)

clinical testing
pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

chave InChI

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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Descrição geral

Biotin is a bicyclic compound, which is widely distributed in food stuffs.[1] It is essentially required as an important nutrient for animals.[1]
Biotin is a water soluble vitamin, which functions as a coenzyme in several carboxylase-mediated metabolic reactions such as gluconeogenesis, biosynthesis of fatty acids, and metabolism of amino acids.[2][3]
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

Aplicação

Biotin may be used as a certified reference material for the quantification of the analyte in food samples, feed, tablets and premixes using high-performance liquid chromatography/avidin binding and high-performance liquid chromatography with tandem mass spectrometry.[2][3]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações legais

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Nutrient Requirements of Dogs and Cats (2006)
Quantification of biotin in feed, food, tablets, and premixes using HPLC?MS/MS
Holler U, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 831(1-2), 8-16 (2006)
Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding
Staggs GC, et al.
J. Food Compos. Anal., 17(6), 767-776 (2004)
Sung Jae Shin et al.
Clinical and vaccine immunology : CVI, 15(8), 1277-1281 (2008-06-14)
We previously reported that protein antigens of serodiagnostic potential were more abundant in culture filtrates than cellular extracts from liquid cultures of Mycobacterium avium subsp. paratuberculosis (D. Cho and M. T. Collins, Clin. Vaccine Immunol. 13:1155-1161, 2006). Based on this
Juha A E Määttä et al.
BMC structural biology, 9, 63-63 (2009-10-01)
Avidins are proteins with extraordinarily high ligand-binding affinity, a property which is used in a wide array of life science applications. Even though useful for biotechnology and nanotechnology, the biological function of avidins is not fully understood. Here we structurally

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