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484407

Sigma-Aldrich

1-Methoxy-2-propanol

greener alternative

≥99.5%

Sinônimo(s):

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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About This Item

Fórmula linear:
CH3CH(OH)CH2OCH3
Número CAS:
107-98-2
Peso molecular:
90.12
Beilstein:
1731270
Número CE:
203-539-1
Número MDL:
MFCD00004537
Código UNSPSC:
12352100
ID de substância PubChem:
57651153
NACRES:
NA.21
Preço e disponibilidade não estão disponíveis no momento.

densidade de vapor

3.12 (vs air)

Nível de qualidade

200

pressão de vapor

10.9 mmHg ( 25 °C)

linha de produto

ReagentPlus®

Ensaio

≥99.5%

Formulário

liquid

temperatura de autoignição

532 °F

Lim. expl.

13.8 %

características do produto alternativo mais ecológico

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impurezas

≤0.001% water

índice de refração

n20/D 1.403 (lit.)

p.e.

118-119 °C (lit.)

pf

-97 °C

solubilidade

water: miscible

densidade

0.916 g/mL at 25 °C (lit.)

aplicação(ões)

microbiology

categoria alternativa mais ecológica

, Aligned

cadeia de caracteres SMILES

CC(O)COC

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

chave InChI

ARXJGSRGQADJSQ-UHFFFAOYSA-N

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Descrição geral

1-Methoxy-2-propanol (Propylene glycol methyl ether, PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.[1] Its degradation by microorganisms in different soil types has been investigated.[2] An oral reference dose (RfD) and an inhalation reference concentration (RfC) values of PGME have been obtained from inhalation studies in F344 rats and B6C3F1 mice.[3]
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry.Monoethers, especially propylene glycol methyl ether (PGME), are widely used as pollution-free solvents in fine chemical synthesis in pharmaceutical, chemical and cosmetic industries and thus aligns with "Safer Solvents and Auxiliaries". Click here for more information.

Informações legais

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

FlameExclamation mark
GHS02,GHS07

Palavra indicadora

Warning

Frases de perigo

H226,H336

Declarações de precaução

P210 - P233 - P240 - P241 - P242 - P243

Classificações de perigo

Flam. Liq. 3 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

88.7 °F - closed cup - (External MSDS)

Ponto de fulgor (°C)

31.5 °C - closed cup - (External MSDS)

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
SDBB2694
STBL4198
MKCW2242
MKCW0598
MKCW1794

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3-Ethoxy-1-propanol 97%

Sigma-Aldrich

E7401

3-Ethoxy-1-propanol

Propylene glycol propyl ether 99%

Sigma-Aldrich

424927

Propylene glycol propyl ether

Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
Juergen Brieger et al.
Toxicology letters, 177(2), 138-143 (2008-02-26)
To evaluate the impact of 1-methoxypropanol-2 (MEP) for the stimulation of an inflammatory response in human respiratory mucosa, we exposed 22 primary cell cultures of nasal respiratory epithelia of healthy individuals to MEP concentrations at the level of the German
S R Vink et al.
Regulatory toxicology and pharmacology : RTP, 58(1), 64-71 (2010-04-17)
REACH requests the exploration of alternative strategies for hazard identification before resorting to (in vivo) testing. Here, we combined read-across as non-testing strategy with a tiered exposure assessment for the risk characterisation of 1-methoxypropan-2-ol (PGME) as a representative for phase-in
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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