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Supelco

Rafoxanide

PESTANAL®, analytical standard

Sinônimo(s):

3′-Chloro-4′-(4-chlorophenoxy)-3,5-diiodosalicylanilide

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100 MG
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100 MG
R$ 1.182,00

About This Item

Fórmula empírica (Notação de Hill):
C19H11Cl2I2NO3
Número CAS:
22662-39-1
Peso molecular:
626.01
Número CE:
245-148-9
Número MDL:
MFCD00682899
Código UNSPSC:
41116107
ID de substância PubChem:
329754777
NACRES:
NA.24

R$ 1.182,00

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grau

analytical standard

Nível de qualidade

100

linha de produto

PESTANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

agriculture
environmental

Formato

neat

cadeia de caracteres SMILES

Oc1c(I)cc(I)cc1C(=O)Nc2ccc(Oc3ccc(Cl)cc3)c(Cl)c2

InChI

1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)

chave InChI

NEMNPWINWMHUMR-UHFFFAOYSA-N

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Descrição geral

Rafoxanide is a halogenated salicylanilide and an anthelmintic agent.[1] It is widely used against fasciolosis and haemonchosis in sheep and cattle.[1] It also finds applications as an adulticide for Fasciola hepatica and Fasciola gigantica.[1]

Aplicação

Rafoxanide may be used as a reference standard in the determination of rafoxanide in plasma and tissue samples using high-performance liquid chromatography (HPLC) coupled with an ultraviolet detector and thermospray − mass spectrometry.[2]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações legais

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCJ7774
BCBZ3293

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J H Boersema et al.
Veterinary parasitology, 68(4), 383-388 (1997-03-01)
A survey was conducted on the occurrence of anthelmintic resistance of trichostrongylids on commercial sheep farms in the highveld of Zimbabwe. On ten farms the efficacy of fenbendazole, levamisole and rafoxanide was tested by a faecal egg count reduction test.
Antonio Di Grazia et al.
Cancers, 12(5) (2020-05-28)
Colorectal cancer (CRC) is a major cause of cancer-related death in the world. Emerging evidence suggests that the clinical success of conventional chemotherapy does not merely rely on cell toxicity, but also results from the restoration of tumor immune surveillance.
Determination of rafoxanide in plasma using high performance liquid chromatography (HPLC) and in tissue using HPLC-thermospray mass spectrometry
Blanchflower J W, et al.
Journal of Liquid Chromatography, 13(8), 1595-1609 (1990)
H Ram et al.
Veterinary research communications, 31(6), 719-723 (2007-02-20)
A trial using albendazole, albendazole plus rafoxanide combination, ivermectin and doramectin was conducted in Pashmina goats having history of fenbendazole resistance to Haemonchus spp. and maintained at high altitude (>2350 m above sea level). Day 0 infection level was variable
J A van Wyk et al.
Veterinary parasitology, 72(2), 157-165 (1997-12-24)
We became increasingly concerned about indications of possible substandard efficacy of some generic anthelmintics, particularly after P.C. van Schalkwyk (personal communication, 1990) had found some batches of imported generic products obtained from international brokers to be poorly active, despite apparently
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