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34176

Supelco

Oxfendazole

VETRANAL®, analytical standard

Sinônimo(s):

Methyl 5-(phenylsulfinyl)-benzimidazol-2-carbamate

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R$ 738,00

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100 MG
R$ 738,00

About This Item

Fórmula empírica (Notação de Hill):
C15H13N3O3S
Número CAS:
53716-50-0
Peso molecular:
315.35
Número CE:
258-714-5
Número MDL:
MFCD00801063
Código UNSPSC:
41116107
ID de substância PubChem:
329754866
NACRES:
NA.24

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grau

analytical standard

Nível de qualidade

100

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

COC(=O)Nc1nc2cc(ccc2[nH]1)S(=O)c3ccccc3

InChI

1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

chave InChI

BEZZFPOZAYTVHN-UHFFFAOYSA-N

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Descrição geral

Oxfendazole is a benzimidazole anthelmintic drug, effective against cysticercosis, echinococcosis and fasciolosis.[1]
Oxfendazole is a member of benzimidazole group of anthelmintics.[2]

Aplicação

Oxfendazole may be used as a reference standard in the determination of oxfendazole in pharmaceutical preparations using reversed-phase high-performance liquid chromatography (RP-HPLC).[3]
Oxfendazole may be used as an analytical reference standard for the determination of the analyte in bovine liver by liquid chromatography method.[4]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Nº do produto
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Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palavra indicadora

Danger

Frases de perigo

H360D,H373,H410

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCL3268
BCCG5828
BCCB2008
BCCB2006
BCBT4620

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L Moreno et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3819-3825 (2012-07-31)
Oxfendazole (OFZ) is efficacious for porcine cysticercosis at 30 mg/kg. OFZ is not registered to be used at this dose. The assessment of the OFZ and metabolites [(fenbendazole sulphone (FBZSO2), fenbendazole (FBZ)] plasma pharmacokinetic and tissue residue profiles after its
C S Sikasunge et al.
Veterinary parasitology, 158(1-2), 57-66 (2008-10-07)
The aim of this study was to assess the effect of treating Taenia solium infected pigs with oxfendazole (OFZ) on viability and clearance of cysticerci and the corresponding persistence of specific antibody isotypes (IgG(total), IgG1, IgG2 and IgA) and circulating
Jihei Nishimura et al.
Archives of toxicology, 84(2), 143-153 (2009-12-25)
To clarify whether enzymatically modified isoquercitrin (EMIQ) or melatonin (MLT) supplementation reduces oxidative stress-mediated hepatocellular tumor-promoting effect of oxfendazole (OX), a benzimidazole anthelmintic, male rats were administered a single intraperitoneal injection of N-diethylnitrosamine (DEN) and were fed a diet containing
Yasuaki Dewa et al.
Archives of toxicology, 81(9), 647-654 (2007-03-07)
The effect of oxfendazole (OX), a benzimidazole anthelmintic, on hepatic gene expression was investigated in the liver of rats as a preliminary study to elucidate the possible mechanism of its non-genotoxic hepatocarcinogenesis. The liver from a male F344/N rat given
Chemotherapy of Gastrointestinal Helminths.
Handbook of Experimental Pharmacology, 77, 111-114 (2012)
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