34003
HMMNI
VETRANAL®, analytical standard
Sinônimo(s):
2-Hydroxymethyl-1-methyl-5-nitro-1H-imidazole
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10 MG
R$ 5.043,00
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10 MG
R$ 5.043,00
About This Item
Fórmula empírica (Notação de Hill):
C5H7N3O3
Número CAS:
Peso molecular:
157.13
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24
Produtos recomendados
grau
analytical standard
Nível de qualidade
linha de produto
VETRANAL®
prazo de validade
limited shelf life, expiry date on the label
técnica(s)
HPLC: suitable
gas chromatography (GC): suitable
aplicação(ões)
forensics and toxicology
pharmaceutical (small molecule)
Formato
neat
cadeia de caracteres SMILES
Cn1c(CO)ncc1[N+]([O-])=O
InChI
1S/C5H7N3O3/c1-7-4(3-9)6-2-5(7)8(10)11/h2,9H,3H2,1H3
chave InChI
JSAQDPJIVQMBAY-UHFFFAOYSA-N
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Descrição geral
HMMNI is a hydroxy metabolite of nitroimidazole antibiotics, belonging to a class of veterinary drugs with therapeutic applications in the treatment and prevention of certain bacterial and protozoal diseases in poultry and swine.[1]
Aplicação
HMMNI may be used as a reference standard for the determination of HMMNI in porcine liver using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).[4]
HMMNI may be used as an analytical reference standard for the determination of the analyte in:
- Different matrices of swine using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)[4] and ultra-performance liquid chromatography coupled to electrospray tandem mass spectrometry (UPLC-ESI-MS/MS).[1]
- Biological & environmental matrices using liquid chromatography with ultraviolet detection (LC-UV).[5]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Produtos recomendados
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Informações legais
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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Nº do produto
Descrição
Preços
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Carc. 2 - Muta. 2
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Analytical methodologies for the determination of nitroimidazole residues in biological and environmental liquid samples: a review.
Mahugo-Santana C, et al.
Analytica Chimica Acta, 665(2), 113-122 (2010)
Determination of dimetridazole in poultry tissues and eggs using liquid chromatography-thermospray mass spectrometry.
Cannavan A and Kennedy GD
Analyst, 122(9), 963-966 (1997)
G Carignan et al.
Journal - Association of Official Analytical Chemists, 71(6), 1146-1149 (1988-11-01)
A study was conducted to monitor the elimination of dimetridazole (DMZ) and its major metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI) in swine plasma and tissue, using a liquid chromatographic method with electrochemical detector sensitive to 0.5 ppb. The study consisted of 2 experiments.
Determination of 5-nitroimidazoles and corresponding hydroxy metabolites in swine kidney by ultra-performance liquid chromatography coupled to electrospray tandem mass spectrometry.
Xia Xi, et al.
Analytica Chimica Acta, 637(1-2), 79-86 (2009)
S Inghelbrecht et al.
Journal of veterinary pharmacology and therapeutics, 19(1), 62-67 (1996-02-01)
The anti-trichomonal efficacy and pharmacokinetics of dimetridazole were investigated in the homing pigeon (Columba livia). Dimetridazole was formulated for drinking water medication and as a prolonged-release tablet. To suppress a Trichomonas gallinae infection successfully, medicated drinking water containing dimetridazole (400
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