247588

Salicylic acid

ACS reagent, ≥99.0%

• Sinônimo(s): 2-Hydroxybenzoic acid
• Fórmula linear: 2^-(HO)C₆H₄CO₂H
• Número CAS: 69-72-7
• Peso molecular: 138.12
• Beilstein: 774890
• Número CE: 200-712-3
• Número MDL: MFCD00002439
• Código UNSPSC: 12352100
• ID de substância PubChem: 24854876
• NACRES: NA.21

Propriedades

• grau: ACS reagent
• Nível de qualidade: 200
• densidade de vapor: 4.8 (vs air)
• pressão de vapor: 1 mmHg ( 114 °C)
• Ensaio: ≥99.0%
• Impurezas: H₂SO₄, passes test (darkened)
• resíduo de ignição: ≤0.01%
• pb: 211 °C (lit.)
• pf: 158-161 °C (lit.)
• traços de ânion: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• traços de cátion: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• cadeia de caracteres SMILES: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• chave InChI: YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Informações sobre genes: human ... ALB(213) , PTPN1(5770)

Descrição

Descrição geral

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Aplicação

Salicylic acid has been used:

• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Ações bioquímicas/fisiológicas

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Informações de segurança

• Pictogramas: GHS08,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302,H318,H361d
• Declarações de precaução: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classificações de perigo: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 314.6 °F - closed cup
• Ponto de fulgor (°C): 157 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves