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103217

Sigma-Aldrich

Lumichrome

Sinônimo(s):

7,8-Dimethylalloxazine

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About This Item

Fórmula empírica (Notação de Hill):
C12H10N4O2
Número CAS:
1086-80-2
Peso molecular:
242.23
Número CE:
214-120-8
Número MDL:
MFCD00005021
Código UNSPSC:
12171500
ID de substância PubChem:
24846599
NACRES:
NA.47

forma

powder, crystals or chunks

pf

>300 °C (lit.)

λmax

350 nm
392 nm (2nd)

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

Cc1cc2nc3NC(=O)NC(=O)c3nc2cc1C

InChI

1S/C12H10N4O2/c1-5-3-7-8(4-6(5)2)14-10-9(13-7)11(17)16-12(18)15-10/h3-4H,1-2H3,(H2,14,15,16,17,18)

chave InChI

ZJTJUVIJVLLGSP-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. It is a flourescent photoproduct of riboflavin degradation. It is known to be an effective photosensitizer and a fluorescent dye.

Aplicação

Lumichrome is suitable as a fluorescence probe, metal ion sensor, and may be used for the inactivation of biological contaminants. Its applications are also seen in memory and semiconductor devices.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number
0000387410
0000373839
0000358934
0000358933
0000373839

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Sigma-Aldrich

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Sigma-Aldrich

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Riboflavina (B2) analytical standard

Supelco

47861

Riboflavina (B2)

(−)-Riboflavina Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1054

(−)-Riboflavina

FICZ ≥95% (HPLC)

Sigma-Aldrich

SML1489

FICZ

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Sigma-Aldrich

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Alloxan monohydrate

Sathish Rajamani et al.
Molecular plant-microbe interactions : MPMI, 21(9), 1184-1192 (2008-08-15)
Many bacteria use quorum sensing (QS) as an intercellular signaling mechanism to regulate gene expression in local populations. Plant and algal hosts, in turn, secrete compounds that mimic bacterial QS signals, allowing these hosts to manipulate QS-regulated gene expression in
Partha Bairi et al.
The journal of physical chemistry. B, 114(35), 11454-11461 (2010-08-19)
Lumichrome (L) and melamine (M) produce thermoreversible hydrogels in LM31 and LM11 compositions, but LM13 composition does not produce hydrogel (the numbers indicate the respective molar ratio of the components). The formation of thermoreversible gels is confirmed from morphology, DSC
Chuan Liu et al.
Journal of cellular physiology, 233(11), 8971-8983 (2018-06-16)
The dynamic balance between bone resorption and bone formation is crucial to maintain bone mass. Osteoclasts are key cells that perform bone resorption while osteoblasts and osteocytes function in bone formation. Osteoporosis, a bone metabolism disease characterized by bone loss
Maria Marchena et al.
The journal of physical chemistry. B, 115(10), 2424-2435 (2011-02-22)
We report on photophysical studies of lumichrome (Lc) in water at different pHs, and interacting with the human serum albumin (HSA) protein and β-cyclodextrin (β-CD) in neutral aqueous solutions. We used steady-state and picosecond time-resolved emission spectroscopy to investigate the
Tamutenda Chidawanyika et al.
mBio, 11(4) (2020-08-14)
Extracellular hydrogen peroxide can induce oxidative stress, which can cause cell death if unresolved. However, the cellular mediators of H2O2-induced cell death are unknown. We determined that H2O2-induced cytotoxicity is an iron-dependent process in HAP1 cells and conducted a CRISPR/Cas9-based
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