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03910590

(±)-Catechin hydrate

primary reference standard

Sinônimo(s):

trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, trans-3,3′,4′,5,7-Pentahydroxyflavane

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About This Item

Fórmula empírica (Notação de Hill):
C15H14O6 · xH2O
Número CAS:
7295-85-4
Peso molecular:
290.27 (anhydrous basis)
Beilstein:
92762
Número CE:
205-825-1
Número MDL:
MFCD00149354
Código UNSPSC:
85151701
ID de substância PubChem:
329747836
NACRES:
NA.24

grau

primary reference standard

Ensaio

>90.0%

Formulário

powder

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

aplicação(ões)

food and beverages

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1

chave InChI

OFUMQWOJBVNKLR-NQQJLSKUSA-N

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Descrição geral

Catechin hydrate, a flavononol, belongs to the class of flavonoids. It is present in abundance in Siberian larch (Larix sibirica) and in silymarin extract of milk thistle seeds. Its potent chemopreventive action by virtue of the regulation of genes through the ARE-dependent pathway has been widely investigated. It also shows potential antioxidant activity against ovarian cancer cell growth, cellular melanogenesis, human breast cancer, etc.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicação

Catechin hydrate may be used as a reference standard for the determination of the analyte in walnut leaves by high-performance liquid chromatography (HPLC).

Ações bioquímicas/fisiológicas

Polyphenolic antioxidant. Used in traditional Chinese medicine.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
HWI01609-2
HWI01609-1
HWI00669-2
HWI01609

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(−)-Epicatechin ≥98% (HPLC), from green tea

Sigma-Aldrich

E4018

(−)-Epicatechin

Ácido gálico certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

91215

Ácido gálico

Ácido clorogênico ≥95% (titration)

Sigma-Aldrich

C3878

Ácido clorogênico

Ácido gálico 97.5-102.5% (titration)

Sigma-Aldrich

G7384

Ácido gálico

HPLC determination of phenolic acids, flavonoids and juglone in walnut leaves
Nour V, et al.
Journal of Chromatographic Science, 51(9) (2013)
R Hursel et al.
Obesity reviews : an official journal of the International Association for the Study of Obesity, 12(7), e573-e581 (2011-03-04)
Different outcomes of the effect of catechin-caffeine mixtures and caffeine-only supplementation on energy expenditure and fat oxidation have been reported in short-term studies. Therefore, a meta-analysis was conducted to elucidate whether catechin-caffeine mixtures and caffeine-only supplementation indeed increase thermogenesis and
T Miyazawa
BioFactors (Oxford, England), 13(1-4), 55-59 (2001-03-10)
Green tea is consumed as a popular beverage in Japan and throughout the world. During the past decade, epidemiological studies have shown that tea catechin intake is associated with lower risk of cardiovascular disease. In vitro biochemical studies have reported
Elena Roura et al.
Clinical chemistry, 52(4), 749-752 (2006-02-14)
Plant polyphenols have been studied largely because of the possibility that they might underlie the protective effects afforded by fruit and vegetable intake against cancer and other chronic diseases. Measurement of polyphenol content excreted in urine as an indicator of
Silvia Mandel et al.
Free radical biology & medicine, 37(3), 304-317 (2004-06-30)
Neurodegeneration in Parkinson's, Alzheimer's, and other neurodegenerative diseases seems to be multifactorial, in that a complex set of toxic reactions including inflammation, glutamatergic neurotoxicity, increases in iron and nitric oxide, depletion of endogenous antioxidants, reduced expression of trophic factors, dysfunction
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