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Key Documents

01700

Sigma-Aldrich

Acrilamida

purum, ≥98.0% (GC)

Sinônimo(s):

2-Propenamida, Amida de ácido acrílico

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About This Item

Fórmula linear:
CH2=CHCONH2
Número CAS:
Peso molecular:
71.08
Beilstein:
605349
Número CE:
Número MDL:
Código UNSPSC:
41105319
eCl@ss:
39031205
ID de substância PubChem:
NACRES:
NB.22

densidade de vapor

2.45 (vs air)

Nível de qualidade

pressão de vapor

0.03 mmHg ( 40 °C)

grau

purum

Ensaio

≥98.0% (GC)

pb

125 °C/25 mmHg (lit.)

pf

81-87 °C
82-86 °C (lit.)

solubilidade

water: soluble 200 g/L at 20 °C

temperatura de armazenamento

room temp

cadeia de caracteres SMILES

NC(=O)C=C

InChI

1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)

chave InChI

HRPVXLWXLXDGHG-UHFFFAOYSA-N

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Aplicação

Acrylamide has been used for preparing slab gel gradients for polyacrylamide gel electrophoresis (PAGE).

Ações bioquímicas/fisiológicas

Acrylamide is a reactive, water soluble vinyl monomer. It causes a decrease in the number of neuritis per cell as well as reduces the rate of protein synthesis.

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral

Órgãos-alvo

Peripheral nervous system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

280.4 °F - closed cup

Ponto de fulgor (°C)

138 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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M W Cunningham et al.
The Journal of experimental medicine, 164(4), 998-1012 (1986-10-01)
mAbs produced by immunization of BALB/c mice with Streptococcus pyogenes M type 5 membranes were further characterized for their reaction with S. pyogenes pep M5 protein and with autoantigens associated with human cell lines. mAbs 36.2.2 and 54.2.8 simultaneously reacted
M Nordin-Andersson et al.
Cell biology and toxicology, 19(1), 43-51 (2003-03-29)
Basal cytotoxicity, morphological changes and alterations in cell physiological and neurochemical functions were studied in differentiated human neuroblastoma (SH-SY5Y) cells during exposure to acrylamide and during a subsequent recovery period after cessation of exposure. Acrylamide induced a 20% reduction in
Arianna Rath et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15668-15673 (2013-09-11)
SDS/PAGE is universally used in biochemistry, cell biology, and immunology to resolve minute protein amounts readily from tissue and cell extracts. Although molecular weights of water-soluble proteins are reliably determined from their SDS/PAGE mobility, most helical membrane proteins, which comprise
Jonas S Laursen et al.
Journal of the American Chemical Society, 135(7), 2835-2844 (2013-01-25)
Non-natural peptide analogs have significant potential for the development of new materials and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β-alanines), has found use in a variety of biologically active compounds but has been sparsely studied with respect to
Janneke G F Hogervorst et al.
Critical reviews in toxicology, 40(6), 485-512 (2010-02-23)
Since 2002, it is known that the probable human carcinogen acrylamide is present in commonly consumed carbohydrate-rich foods, such as French fries and potato chips. In this review, the authors discuss the body of evidence on acrylamide carcinogenicity from both

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