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Merck
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Documentos

19-4497

Sigma-Aldrich

Metronidazole

SAJ first grade, ≥99.0%

Sinônimo(s):

2-Methyl-5-nitroimidazole-1-ethanol

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About This Item

Fórmula empírica (Notação de Hill):
C6H9N3O3
Número CAS:
443-48-1
Peso molecular:
171.15
Beilstein:
611683
Número CE:
207-136-1
Número MDL:
MFCD00009750
Código UNSPSC:
12352005
ID de substância PubChem:
329751879

grau

SAJ first grade

Ensaio

≥99.0%

forma

solid

disponibilidade

available only in Japan

pf

159-161 °C (lit.)

espectro de atividade do antibiótico

Gram-negative bacteria
parasites

Modo de ação

DNA synthesis | interferes

cadeia de caracteres SMILES

CC1=NC=C([N+]([O-])=O)N1CCO

InChI

1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3

chave InChI

VAOCPAMSLUNLGC-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Chemical structure: imidazole

Pictogramas

Health hazard
GHS08

Palavra indicadora

Danger

Frases de perigo

H340,H350,H373

Classificações de perigo

Carc. 1B - Muta. 1B - STOT RE 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Christina M Surawicz et al.
The American journal of gastroenterology, 108(4), 478-498 (2013-02-27)
Clostridium difficile infection (CDI) is a leading cause of hospital-associated gastrointestinal illness and places a high burden on our health-care system. Patients with CDI typically have extended lengths-of-stay in hospitals, and CDI is a frequent cause of large hospital outbreaks
T H I Brummer et al.
BJOG : an international journal of obstetrics and gynaecology, 120(10), 1269-1276 (2013-06-22)
To evaluate cefuroxime and metronidazole antibiotic prophylaxis. Observational nonrandomised 1-year prospective cohort study. Fifty-three hospitals in Finland. A total of 5279 women undergoing hysterectomy for benign indications, with cefuroxime given to 4301 and metronidazole given to 2855. Excluding other antibiotics
Dina Zandbergen et al.
Journal of periodontology, 84(3), 332-351 (2012-05-23)
The treatment of periodontitis frequently begins with a non-surgical phase that includes scaling and root planing (SRP) and, on occasion, the use of systemic antibiotics. The goal of this review is to systematically evaluate the data concerning the effect of
Sonja Löfmark et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 50 Suppl 1, S16-S23 (2010-01-14)
Metronidazole has been used for the treatment of infections for >45 years and is still successfully used for the treatment of trichomoniasis, amoebiasis, and giardiasis. Anaerobic bacterial infections caused by Bacteroides species, fusobacteria, and clostridia respond favorably to metronidazole therapy.
Konstantinos Z Vardakas et al.
International journal of antimicrobial agents, 40(1), 1-8 (2012-03-09)
The objective of this review was to evaluate the frequency of treatment failure and recurrence of Clostridium difficile infection (CDI) following treatment with vancomycin or metronidazole in recently performed studies (last 10 years). Searches in PubMed and Scopus were performed
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