MABN92-AF647
Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor™ 647 Conjugate
clone 20A12.1, from mouse, ALEXA FLUOR™ 647
Sinônimo(s):
Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.45
Preço e disponibilidade não estão disponíveis no momento.
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
conjugado
ALEXA FLUOR™ 647
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
20A12.1, monoclonal
reatividade de espécies
mouse, human, rat
técnica(s)
immunofluorescence: suitable
Isotipo
IgG1κ
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... AIF1(199)
Descrição geral
Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.
Aplicação
Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor™ 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence.
The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.
Qualidade
Evaluated by Immunofluorescence in human spleen tissue.
Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.
Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.
Descrição-alvo
~17 kDa observed.
Outras notas
Concentration: Please refer to lot specific datasheet.
Informações legais
ALEXA FLUOR is a trademark of Life Technologies
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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