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MABN738

Sigma-Aldrich

Anti-OCT6 Antibody, clone KT110

clone KT110, from mouse

Sinônimo(s):

POU domain, class 3, transcription factor 1, Octamer-binding protein 6, Oct-6, Octamer-binding transcription factor 6, OTF-6, POU domain transcription factor SCIP

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

KT110, monoclonal

reatividade de espécies

mouse, human

técnica(s)

electrophoretic mobility shift assay: suitable
immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG1κ

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

Descrição geral

Octamer-binding protein 6 (Oct-6) is also called POU domain, class 3, transcription factor 1 (Pou3f1), Octamer-binding transcription factor 6 (OTF-6) and POU domain transcription factor SCIP. Oct-6 is a transcription factor that specifically binds to the (5′-ATTTGCAT-3′) octamer motif. Oct-6 has been implicated in early embryogenesis, neurogenesis, keratinocyte differentiation and myelination in the peripheral nervous system.

Imunogênio

Recombinant protein corresponding to mouse OCT6.

Aplicação

Anti-OCT6 Antibody, clone KT110 is a highly specific mouse monoclonal antibody, that targets Oct-6 & has been tested in western blotting, IHC & Electrophoretic Mobility Shift Assay.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected OCT6 in mouse embryonic brain (D15.5) tissue.
Electophoretic Mobility Shift Assay (EMSA) Analysis: A representative lot detected SphK1 in nuclear extracts from RT4 Schwannoma or primay rat Shcwann cells (Prof. D. Meijer, Erasmus University Medical Center, Rotterdam.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

Qualidade

Evaluated by Western Blotting in H9 human embreyonic stem cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected OCT6 in 10 µg of H9 human embreyonic stem cell lysate.

Descrição-alvo

~50 kDa observed

Ligação

Replaces: MABN1060

forma física

Format: Purified
Protein A purified
Purified mouse monoclonal IgG1κ in buffer containing PBS and 0.9% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Vittoria Dickinson Bocchi et al.
Science (New York, N.Y.), 372(6542) (2021-05-08)
Deciphering how the human striatum develops is necessary for understanding the diseases that affect this region. To decode the transcriptional modules that regulate this structure during development, we compiled a catalog of 1116 long intergenic noncoding RNAs (lincRNAs) identified de
Joshua Po Han Wu et al.
Frontiers in molecular neuroscience, 15, 921901-921901 (2022-08-09)
The cerebellar nuclear (CN) neurons are a molecularly heterogeneous population whose specification into the different cerebellar nuclei is defined by the expression of varying sets of transcription factors. Here, we present a novel molecular marker, Pou3f1, that delineates specific sets
Michel Fries et al.
Cell reports, 42(8), 112985-112985 (2023-08-17)
The balance of contralateral and ipsilateral retinogeniculate projections is critical for binocular vision, but the transcriptional programs regulating this process remain ill defined. Here we show that the Pou class homeobox protein POU3F1 is expressed in nascent mouse contralateral retinal
Masaki Kinoshita et al.
Cell stem cell, 28(3), 453-471 (2020-12-04)
Pluripotent cells emerge as a naive founder population in the blastocyst, acquire capacity for germline and soma formation, and then undergo lineage priming. Mouse embryonic stem cells (ESCs) and epiblast-derived stem cells (EpiSCs) represent the initial naive and final primed
Sophie M Morgani et al.
Methods in molecular biology (Clifton, N.J.), 2214, 41-58 (2020-09-19)
Pluripotent stem cells (PSCs) are the in vitro counterpart of the pluripotent epiblast of the mammalian embryo with the capacity to generate all cell types of the adult organism. During development, the three definitive germ layers are specified and simultaneously

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