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MAB2023Z

Sigma-Aldrich

Anti-Integrin beta 3 (ITGB3/CD61) Antibody

CHEMICON®, mouse monoclonal, B3A

Sinônimo(s):

CD61, MAB2023

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

Nome do produto

Anti-Integrin β3 Antibody, clone B3A, azide free, clone B3A, Chemicon®, from mouse

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

B3A, monoclonal

reatividade de espécies

human

fabricante/nome comercial

Chemicon®

técnica(s)

flow cytometry: suitable
western blot: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... ITGB3(3690)

Especificidade

Specific for human integrin beta 3 (other species not tested).

Imunogênio

Human integrin alphaVbeta3 heterodimer isolated from placenta.

Aplicação

Anti-Integrin β3 Antibody, clone B3A, azide free detects level of Integrin β3 & has been published & validated for use in FC, FUNC & WB.
Flow cytometry

Function-blocking of integrin beta3-mediated adhesion to ECM proteins.

Western blot (reducing conditions) Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Descrição-alvo

110 kDa

forma física

Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
Protein A purified

Armazenamento e estabilidade

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análise

Control
Positive Control: U251 or D54 human cell lines. Membrane preps are recommended for western blots.
Human endothelium cells (expression of integrin alpha V beta 3 may need to be upregulated by phorbol esters stimulation). Skin (Basement Membrane)

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Molecular cancer, 9, 130-130 (2010-06-01)
Lung cancer is one of the most prevalent neoplasias in developed countries. Advances in patient survival have been limited and the identification of prognostic molecules is needed. Resistance to treatment is strongly related to tumor cell adhesion to the extracellular
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PloS one, 12(2), e0171417-e0171417 (2017-02-07)
Microfluidic devices are becoming mainstream tools to recapitulate in vitro the behavior of cells and tissues. In this study, we use microfluidic devices filled with hydrogels of mixed collagen-Matrigel composition to study the migration of lung cancer cells under different
Clementina Auriemma et al.
Cellular & molecular biology letters, 15(3), 496-506 (2010-06-08)
Listeria monocytogenes enters non-phagocytic cells by binding its surface proteins inlA (internalin) and inlB to the host's E-cadherin and Met, respectively. The two internalins play either separate or cooperative roles in the colonization of infected tissues. Here, we studied bacterial
Ann-Marie Baker et al.
Journal of the National Cancer Institute, 103(5), 407-424 (2011-02-02)
Emerging evidence implicates lysyl oxidase (LOX), an extracellular matrix-modifying enzyme, in promoting metastasis of solid tumors. We investigated whether LOX plays an important role in the metastasis of colorectal cancer (CRC). We analyzed LOX expression in a patient CRC tissue

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