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Documentos Principais

MAB1476

Sigma-Aldrich

Anti-Chymotrypsin Antibody, Human Pancreas

ascites fluid, Chemicon®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

fonte biológica

mouse

forma do anticorpo

ascites fluid

tipo de produto de anticorpo

primary antibodies

clone

monoclonal

reatividade de espécies

human

fabricante/nome comercial

Chemicon®

técnica(s)

ELISA: suitable
immunohistochemistry: suitable

Isotipo

IgG3

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Descrição geral

Chymotrypsin is an intestinal proteolytic enzyme composed of three polypeptide chains. It is produced in the pancrease as the inactive form chymotrypsinogen (single 245 aa chain). Chymotrypsinogen is activated in the duodenum by trypin and other active chymotrypsin molecules. It preferentially catalyzes the hydrolysis of peptide bonds involving L-isomers of tyrosine, phenylalanine and tryptophan. It also readily acts upon amides and esters of susceptible amino acids. Chymotrypsin catalyzes the hydrolysis of bonds of leucyl, methionyl, asparaginyl and glutamyl residues.

Especificidade

Recognizes chymotrypsin.

Imunogênio

Purified human pancreatic chymotrypsin.

Aplicação

Detect Chymotrypsin using this Anti-Chymotrypsin Antibody, Human Pancreas validated for use in ELISA, IH.
ELISA

Immunohistochemistry: 1:1000.

Optimal working dilution must be determined by the end user.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry

forma física

Liquid. Contains no preservative.

Armazenamento e estabilidade

Maintain at -20°C in convenient aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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COVID-19 pandemic has infected more than 154 million people worldwide and caused more than 3.2 million deaths. It is transmitted by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and affects the respiratory tract as well as extra-pulmonary systems, including
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Cancer cytopathology, 121(8), 459-470 (2013-02-15)
Acinar cell neoplasms of the pancreas are rare but when encountered, the diagnosis is often established based on cytology specimens. Diagnostic accuracy is important because acinar cell carcinomas are aggressive yet may mimic tumors with different outcomes and management. The
Markus Breunig et al.
Cell stem cell, 28(6), 1105-1124 (2021-04-30)
Personalized in vitro models for dysplasia and carcinogenesis in the pancreas have been constrained by insufficient differentiation of human pluripotent stem cells (hPSCs) into the exocrine pancreatic lineage. Here, we differentiate hPSCs into pancreatic duct-like organoids (PDLOs) with morphological, transcriptional, proteomic

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