ABN462
Anti-Dopamine D2 Receptor Antibody
from rabbit, purified by affinity chromatography
Sinônimo(s):
Dopamine D2 Receptor, D2R
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
purificado por
affinity chromatography
reatividade de espécies
mouse
técnica(s)
immunohistochemistry: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
mouse ... Drd2(13489)
Descrição geral
The Dopamine D2 Receptor is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. 2 isoforms are reported for the D2 Dopamine Receptor, Isoform 1 and isoform 2 which are expressed in the pituitary and brain; Isoform 1 is expressed seven times more than isoform 2 in the caudate nucleus.
Especificidade
This antibody binds to the cytoplasmic third intracellular loop.
Imunogênio
Epitope: cytoplasmic third intracellular loop
Recombinant protein corresponding to the cytoplasmic domain of mouse Dopamine D2 Receptor.
Aplicação
Anti-Dopamine D2 Receptor Antibody is an antibody against Dopamine D2 Receptor for use in Immunohistochemistry.
Immunohistochemistry Analysis: A representative lot detected Dopamine D2 Receptor in WT mouse striatum tissue (Trifilieff, P., et al. (2013). Molecular Psychiatry. 18:102-1033).
Immunohistochemistry Analysis: A representative lot detected Dopamine D2 Receptor in wild-type and not in D2R knockout mouse sriatum tissue (Trifilieff, P., et al. (2011). BioTechniques. 50:111-118).
Immunohistochemistry Analysis: A representative lot detected Dopamine D2 Receptor in wild-type and not in D2R knockout mouse sriatum tissue (Trifilieff, P., et al. (2011). BioTechniques. 50:111-118).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
Qualidade
Evaluated by Immunohistochemistry in mouse striatum tissue.
Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Dopamine D2 Receptor in mouse striatum tissue.
Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Dopamine D2 Receptor in mouse striatum tissue.
Descrição-alvo
50.9 kDa calculated
forma física
Affinity
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Armazenamento e estabilidade
Stable for 1 year at 2-8°C from date of receipt.
Outras notas
Concentration: Please refer to lot specific datasheet.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Jérôme Jeanblanc et al.
Brain : a journal of neurology (2024-05-05)
The use of psilocybin to treat alcohol use disorder is very promising, but the mechanisms of action remain poorly understood. We combined behavioral, pharmacological and gene expression analyses to decipher the mechanisms of action of psilocybin, for the first time
Ying Zhu et al.
BioTechniques, 68(3), 122-129 (2019-12-21)
Despite the controversy regarding the existence and physiological relevance of class A G protein-coupled receptor dimerization, there is substantial evidence for functional interactions between the dopamine D2 receptor (D2R) and the adenosine A2A receptor (A2AR). A2AR-D2R complexes have been detected in
Andry Andrianarivelo et al.
Science advances, 7(43), eabg5970-eabg5970 (2021-10-21)
[Figure: see text].
Benjamin Lassus et al.
Scientific reports, 8(1), 17461-17461 (2018-12-01)
Although the prefrontal cortex and basal ganglia are functionally interconnected by parallel loops, cellular substrates underlying their interaction remain poorly understood. One novel approach for addressing this issue is microfluidics, a methodology which recapitulates several intrinsic and synaptic properties of
Ying Zhu et al.
Current protocols in neuroscience, 91(1), e86-e86 (2020-01-17)
Combining immunological and molecular biological methods, the antibody-based proximity ligation assay (PLA) has been used for more than a decade to detect and quantify protein-protein interactions, protein modification, and protein expression in situ, including in brain tissue. However, the transfer
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