ABN174
Anti-MNX1 (HB9) Antibody
from rabbit, purified by affinity chromatography
Sinônimo(s):
Motor neuron and pancreas homeobox protein 1, Homeobox protein HB9
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
purificado por
affinity chromatography
reatividade de espécies
mouse, human
técnica(s)
immunohistochemistry: suitable
western blot: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... MNX1(3110)
Descrição geral
Motor neuron and pancreas homeobox protein 1 (MNX1) is a transcription factor that is predominantly expressed in lymphoid and pancreatic tissues. It is involved in the development and function of the pancreas. Abnormal expression of MNX1 results in an autosomal dominant condition known as Currarino syndrome.
Especificidade
Other homologies: Zebrafish (94% sequence homology) and Xenopus (89% sequence homology).
This antibody recognizes a portion of the Homeobox DNA binding domain.
Imunogênio
KLH-conjugated linear peptide corresponding to human MNX1.
Aplicação
Anti-MNX1 (HB9) Antibody detects level of MNX1 (HB9) & has been published & validated for use in Western Blotting & IHC.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected MNX1 in human pancreas and mouse cerebral cortex tissues.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Transcription Factors
Transcription Factors
Qualidade
Evaluated by Western Blot in PANC-1 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected MNX1 in 10 µg of PANC-1 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected MNX1 in 10 µg of PANC-1 cell lysate.
Descrição-alvo
~50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.
forma física
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Armazenamento e estabilidade
Stable for 1 year at 2-8°C from date of receipt.
Nota de análise
Control
PANC-1 cell lysate
PANC-1 cell lysate
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Ferramenta de seleção de produtos.
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Daehwan Kim et al.
Translational neurodegeneration, 11(1), 16-16 (2022-03-12)
Amyotrophic lateral sclerosis (ALS) is characterized by a progressive loss of motor neurons (MNs), leading to paralysis, respiratory failure and death within 2-5 years of diagnosis. The exact mechanisms of sporadic ALS, which comprises 90% of all cases, remain unknown. In
G Perez-Siles et al.
Scientific reports, 10(1), 9262-9262 (2020-06-07)
Charcot-Marie-Tooth (CMT) is a group of inherited diseases clinically and genetically heterogenous, characterised by length dependent degeneration of axons of the peripheral nervous system. A missense mutation (p.R158H) in the pyruvate dehydrogenase kinase 3 gene (PDK3) has been identified as
Gonzalo Perez-Siles et al.
Disease models & mechanisms, 13(2) (2020-01-24)
ATP7A encodes a copper-transporting P-type ATPase and is one of 23 genes in which mutations produce distal hereditary motor neuropathy (dHMN), a group of diseases characterized by length-dependent axonal degeneration of motor neurons. We have generated induced pluripotent stem cell
Toma Tebaldi et al.
Molecular cell, 71(2), 256-270 (2018-07-22)
The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral axon injury. HuD interacts with many mRNAs, altering both stability and translation efficiency. We generated a nucleotide resolution map of the HuD RNA interactome in motor neuron-like cells, identifying
Ilary Allodi et al.
Scientific reports, 6, 25960-25960 (2016-05-18)
The fatal disease amyotrophic lateral sclerosis (ALS) is characterized by the loss of somatic motor neurons leading to muscle wasting and paralysis. However, motor neurons in the oculomotor nucleus, controlling eye movement, are for unknown reasons spared. We found that
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica