1.00631

Salicylic acid

EMPROVE^® ESSENTIAL Ph Eur,BP,USP

• Sinônimo(s): Salicylic acid, 2-Hydroxybenzoic acid
• Fórmula empírica (Notação de Hill): C₇H₆O₃
• Número CAS: 69-72-7
• Peso molecular: 138.12
• Número MDL: MFCD00002439
• Código UNSPSC: 12352106
• Número do índice EC: 200-712-3

Propriedades

• Agency: BP; Ph. Eur.; USP
• Nível de qualidade: 500
• pressão de vapor: <1 hPa ( 100 °C)
• linha de produto: EMPROVE^® ESSENTIAL
• Ensaio: 98.0-102.0% dry basis (HPLC)
• forma: solid
• temperatura de autoignição: 500 °C
• potência: 1250-1580 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• técnica(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 2.4 ( in H₂O, saturated solution)
• pb: 211 °C/1013 hPa
• pf: 157-159 °C
• temperatura de transição: flash point 157 °C
• solubilidade: 2 g/L
• densidade: 1.443 g/cm³ at 20 °C
• densidade volumétrica: 400‑500 kg/m³
• traços de ânion: chloride (Cl^-): ≤0.0100%; sulfate (SO₄^2-): ≤0.0200%
• aplicação(ões): liquid formulation; pharmaceutical
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• chave InChI: YGSDEFSMJLZEOE-UHFFFAOYSA-N

Descrição

Descrição geral

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

Salicylic acid is used in dermatological medicine for skin exfoliating and acne. Salicylic acid Emprove^® Essential is suitable for pharmaceutical applications.

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS08,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302,H318,H361d
• Declarações de precaução: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classificações de perigo: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 314.6 °F - closed cup
• Ponto de fulgor (°C): 157 °C - closed cup