N-911

Nordiazepam-d₅ solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (Notação de Hill): C₁₅D₅H₆ClN₂O
• Número CAS: 65891-80-7
• Peso molecular: 275.74
• Número CE: 200-659-6
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: certified reference material
• forma: liquid
• embalagem: ampule of 1 mL
• fabricante/nome comercial: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• concentração: 1 mg/mL in methanol
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): clinical testing
• formato: single component solution
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [2H]c1c([2H])c([2H])c(c([2H])c1[2H])C2=NCC(=O)Nc3ccc(Cl)cc23
• InChI: 1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)/i1D,2D,3D,4D,5D
• chave InChI: AKPLHCDWDRPJGD-RALIUCGRSA-N

Descrição

Descrição geral

Nordiazepam is a benzodiazepine prescribed for treatment of anxiety and panic attacks. This stable-labeled internal standard is suited for quantitation of nordiazepam levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis or isotope dilution methods. Nordiazepam is also a primary urinary metabolite of benzodiazepines diazepam and chlrodiazepoxide.

Aplicação

• Development of UPLC-MS/MS Screening for Psychoactive Drugs: Nordiazepam-d5 was utilized in the development and validation of a rapid ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. This method effectively detects 68 psychoactive drugs and metabolites in whole blood, demonstrating its application in forensic toxicology and post-mortem analysis, enhancing drug metabolism studies and analytical testing capabilities (Barone et al., 2023).

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H225,H301 + H311 + H331,H370
• Declarações de precaução: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órgãos-alvo: Eyes
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 49.5 °F - closed cup
• Ponto de fulgor (°C): 9.7 °C - closed cup