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N-031

Supelco

Norfentanyl oxalate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C14H20N2O · C2H2O4
Número CAS:
1211527-24-0
Peso molecular:
322.36
Número CE:
200-659-6
Número MDL:
MFCD08272799
Código UNSPSC:
41116107
ID de substância PubChem:
329818426
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

certified reference material

Nível de qualidade

300

Formulário

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

concentração

1.0 mg/mL in methanol (as free base)

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

forensics and toxicology

Formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC(=O)C(O)=O.CCC(=O)N(C1CCNCC1)c2ccccc2

InChI

1S/C14H20N2O.C2H2O4/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13;3-1(4)2(5)6/h3-7,13,15H,2,8-11H2,1H3;(H,3,4)(H,5,6)

chave InChI

OLFNESLXXQCODF-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. This Certified Spiking Solution® is suitable for numerous GC/MS or LC/MS testing applications from clinical toxicology and forensic analysis to urine drug testing and pain prescription monitoring.

Informações legais

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Resp. Sens. 1 - STOT SE 1

Órgãos-alvo

Eyes,Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number

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Vera Coopman et al.
Forensic science international, 169(2-3), 223-227 (2006-05-03)
Fentanyl is a potent synthetic narcotic analgesic administered in the form of a transdermal patch for the management of chronic pain. A 78-year-old woman with a history of cancer was found dead in bed. She was lying on her back.
D E Feierman et al.
Drug metabolism and disposition: the biological fate of chemicals, 24(9), 932-939 (1996-09-01)
The microsomal metabolism of fentanyl, a synthetic opioid commonly used in anesthesia, was investigated in human liver. Incubation of fentanyl with human hepatic microsomes fortified with NADPH resulted in the formation of a single major metabolite, namely norfentanyl, as determined
A K Valaer et al.
Journal of chromatographic science, 35(10), 461-466 (1997-10-23)
A sensitive, specific urinary assay for fentanyl, sufentanil, and alfentanil based on their N-dealkylated metabolites is described. Norfentanyl, norsufentanil-noralfentanil, and 2H5-norfentanyl are synthesized and characterized by standard analytical techniques. Derivatization of these secondary amines to yield the pentafluorobenzamides produces stable
Henry J Carson et al.
Legal medicine (Tokyo, Japan), 12(3), 157-159 (2010-04-07)
We recently encountered a subject who died from an uncommon misuse of a fentanyl transdermal patch, chewing, followed by complications of aspiration of the patch. We report this case to alert medical examiners to the troubling trend of increased fentanyl
Ming Jin et al.
Journal of analytical toxicology, 29(7), 590-598 (2006-01-20)
Pharmacogenomics, the study on genetic contributions to drug action may help in certifying fentanyl toxicity. Fentanyl is used clinically as an adjunct to surgical anesthesia and for chronic pain management. Its toxicity may be partially due to cytochrome P450 (CYP)
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Questions

  1. I'm interested in Fentanyl abuse test using urine specimen. Would this product work as positive control for this diagnostic test?

    1 answer

    1. Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. Therefore, this Certified Spiking Solution is suitable for testing applications from clinical toxicology and forensic analysis to urine drug testing. So it can be used as a positive control for urinal drug testing.

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