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860533P

Avanti

C16 Ceramide-1-Phosphate (d18:1/16:0)

Avanti Research™ - A Croda Brand 860533P, powder

Sinônimo(s):

N-palmitoyl-ceramide-1-phosphate (ammonium salt)

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1 MG
R$ 875,00

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R$ 875,00

About This Item

Fórmula empírica (Notação de Hill):
C34H71N2O6P
Número CAS:
1246303-22-9
Peso molecular:
634.91
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 875,00

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Formulário

powder

embalagem

pkg of 1 × 1 mg (860533P-1mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 860533P

tipo de lipídio

sphingolipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(O)=O.[NH4+]

InChI

1S/C34H68NO6P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(36)32(31-41-42(38,39)40)35-34(37)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h27,29,32-33,36H,3-26,28,30-31H2,1-2H3,(H,35,37)(H2,38,39,40);1H3/b29-27+;/t32-,33+;/m0./s1

chave InChI

RCRVTEZMCBPWGN-YWBCJBABSA-N

Descrição geral

C16 Ceramide-1-Phosphate (d18:1/16:0) or N-palmitoyl-ceramide-1-phosphate is a natural long chain ceramide.[1]

Aplicação

C16 Ceramide-1-Phosphate (d18:1/16:0) or N-palmitoyl-ceramide-1-phosphate has been used in lipid preparation to treat endothelial colony-forming cells (ECFCs) for nuclear morphology analysis.[1] It has also been used as a bioactive lipid in cell migration assay to study its effects on multipotent stromal cell (MSCs) and human umbilical vein endothelial cells (HUVECs).[2]

Embalagem

5 mL Amber Glass Screw Cap Vial (860533P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

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Certificados de análise (COA)

Lot/Batch Number

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Albumina sérica bovina 10% in DPBS, low endotoxin, fatty acid free, suitable for cell culture, sterile-filtered

Sigma-Aldrich

A1595

Albumina sérica bovina

Chihwa Kim et al.
Stem cells (Dayton, Ohio), 31(3), 500-510 (2012-11-30)
Ceramide-1-phosphate (C1P) is a bioactive lipid that, in contrast to ceramide, is an antiapoptotic molecule released from cells that are damaged and "leaky." As reported recently, C1P promotes migration of hematopoietic cells. In this article, we tested the hypothesis that
Hebe Agustina Mena et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(10), e219-e232 (2019-08-23)
Ceramide 1-phosphate (C1P) is a bioactive sphingolipid highly augmented in damaged tissues. Because of its abilities to stimulate migration of murine bone marrow-derived progenitor cells, it has been suggested that C1P might be involved in tissue regeneration. In the present
Antonio Gómez-Muñoz et al.
Journal of lipid research, 45(1), 99-105 (2003-10-03)
It was reported previously that ceramide-1-phosphate (Cer-1-P) is mitogenic for fibroblasts (Gómez-Muñoz, A., P. A. Duffy, A. Martin, L. O'Brien, H-S. Byun, R. Bittman, and D. N. Brindley. 1995. Mol. Pharmacol. 47: 883-889; Gómez-Muñoz, A., L. M. Frago, L. Alvarez
V T Hinkovska-Galcheva et al.
The Journal of biological chemistry, 273(50), 33203-33209 (1998-12-05)
Ceramide, a product of agonist-stimulated sphingomyelinase activation, is known to be generated during the phagocytosis of antibody-coated erythrocytes by polymorphonuclear leukocytes. Agonist-stimulated formation of ceramide-1-phosphate is now shown to occur in 32PO4-labeled neutrophils. Ceramide-1-phosphate is formed by a calcium-dependent ceramide
A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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