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857501P

Avanti

16:0-17:0 cyclo PC

Avanti Research™ - A Croda Brand 857501P, powder

Sinônimo(s):

1-palmitoyl-2-cis-9,10-methylenehexadecanoyl-sn-glycero-3-phosphocholine

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1 MG
R$ 746,00

R$ 746,00

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R$ 746,00

About This Item

Fórmula empírica (Notação de Hill):
C41H80NO8P
Número CAS:
2456348-66-4
Peso molecular:
746.05
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 746,00

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Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 1 mg (857501P-1mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 857501P

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC1C(C1)CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

chave InChI

MHMMFIIAMURXQM-DFCGPKRUSA-N

Descrição geral

16:0-17:0 cyclo PC or 1-palmitoyl-2-cis-9,10-methylenehexadecanoyl-sn-glycero-3-phosphocholine is a cyclopropane modified analog of PC.[1] It is a glycerophospholipid and is the most important constituent of the eukaryotic cell membrane.[2][3] Generally, it constitutes up to 40-50% of the cells and organelles.[3]

Ações bioquímicas/fisiológicas

Phosphatidylcholine (PC) is crucial for the synthesis of second messengers and lipid mediators. It also acts as an intermediate for the synthesis of other glycerophospholipid classes along with phosphatidylethanolamine (PE).[2] Any disturbance in PC levels leads to various metabolic disorders.[2]

Embalagem

5 mL Amber Glass Screw Cap Vial (857501P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

No data available

Ponto de fulgor (°C)

No data available

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Certificados de análise (COA)

Lot/Batch Number

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Selma Maric et al.
Applied microbiology and biotechnology, 99(1), 241-254 (2014-10-11)
Phosphatidylcholine (PC) is a major component of eukaryotic cell membranes and one of the most commonly used phospholipids for reconstitution of membrane proteins into carrier systems such as lipid vesicles, micelles and nanodiscs. Selectively deuterated versions of this lipid have
Lian Shan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 864(1-2), 22-28 (2008-02-12)
Lysophosphatidic acid (LPA) is a class of lipids that play multiple biological functions. Several reports show that they are potential biomarkers for diagnosing ovarian cancer. Therefore, it is necessary to accurately quantify their levels in biological samples. Here we report
Nicholas C Zitomer et al.
The Journal of biological chemistry, 284(8), 4786-4795 (2008-12-20)
Fumonisin B(1) (FB(1)) is a mycotoxin that inhibits ceramide synthases (CerS) and causes kidney and liver toxicity and other disease. Inhibition of CerS by FB(1) increases sphinganine (Sa), Sa 1-phosphate, and a previously unidentified metabolite. Analysis of the latter by
Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that
Jelske N van der Veen et al.
Biochimica et biophysica acta. Biomembranes, 1859(9 Pt B), 1558-1572 (2017-04-16)
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis. In recent
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