8.55001

Rink Amide resin (100-200 mesh)

Novabiochem^®

• Sinônimo(s): 4-(2′,4′-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxy resin
• Código UNSPSC: 12352111
• NACRES: NA.22

Propriedades

• Nível de qualidade: 400
• linha de produto: Novabiochem^®
• forma: beads
• adequação da reação: reaction type: Fmoc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• aplicação(ões): peptide synthesis
• grupo funcional: amine
• temperatura de armazenamento: 2-30°C

Descrição

Descrição geral

An excellent support for the Fmoc SPPS of peptide amides. This resin is more acid-sensitive than Rink Amide AM and Rink Amide MBHA resins. Cleavage with high concentrations of TFA can lead to the breakdown of the linker, with the concomitant formation of by-products that can not be removed by simple washes. These problems appear to be minimized through the use of low TFA concentrations or by the addition of trialkyl silanes to the cleavage mixture.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Ligação

Replaces: 01-64-0013

Nota de análise

Color (visual): white to pale yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH₂Cl₂): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/g
The polymer matrix is copoly (styrene-1 % DVB) 100 - 200 mesh.

Informações legais

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable