Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

Visualizar Toda a Documentação

860641P

Avanti

Sphingosine-1-Phosphate (d17:1)

Avanti Research™ - A Croda Brand

Sinônimo(s):

D-erythro-sphingosine-1-phosphate (C17 base)

Faça loginpara ver os preços organizacionais e de contrato

Selecione um tamanho

1 MG
R$ 1.154,00
5 MG
R$ 4.800,00

R$ 1.154,00

Check Cart for Availability
Solicite uma grande encomenda
Todas as fotos(1)

Selecione um tamanho

Alterar visualização
1 MG
R$ 1.154,00
5 MG
R$ 4.800,00

About This Item

Fórmula empírica (Notação de Hill):
C17H36NO5P
Número CAS:
474923-27-8
Peso molecular:
365.45
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 1.154,00

Check Cart for Availability
Solicite uma grande encomenda

Formulário

powder

embalagem

pkg of 1 × 1 mg (860641P-1mg)
pkg of 1 × 5 mg (860641P-5mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand

tipo de lipídio

sphingolipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1

chave InChI

VITGNIYTXHNNNE-LHMZYYNSSA-N

Descrição geral

Sphingosine-1-Phosphate (S1P) (d17:1) is a derivate of ceramide.[1] It is a phosphorylated form of C17 analog of sphingosine.[2] S1P is a zwitterionic sphingolipid. It is found in insects, yeasts and plants.

Aplicação

Sphingosine-1-Phosphate (d17:1) has been used as an internal standard to quantify sphingosine 1-phosphate (S1P) in biological materials and tissue samples by mass spectrometry.[3][4][5]

Ações bioquímicas/fisiológicas

Sphingosine-1-phosphate (S1P) contributes to cellular growth and function.[1] It also aids in various physiological and cellular processes such as atherosclerosis, inflammation, immunity, tumorigenesis and cell proliferation.[2] S1P acts as a signaling lipid in animal cells.

Embalagem

5 mL Amber Glass Screw Cap Vial (860641P-1mg)
5 mL Amber Glass Screw Cap Vial (860641P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Se precisar de ajuda, entre em contato Atendimento ao cliente

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 8

1 of 8

sphingosine-1-phosphate-d7 Avanti Research™ - A Croda Brand

Avanti

860659P

sphingosine-1-phosphate-d7

Sphingosine 1-phosphate ≥95%, powder

Sigma-Aldrich

S9666

Sphingosine 1-phosphate

Sphingosine 1-phosphate ≥98.0% (TLC)

Sigma-Aldrich

73914

Sphingosine 1-phosphate

C18 Ceramide (d17:1/18:0) Avanti Research™ - A Croda Brand 860646P, powder

Avanti

860646P

C18 Ceramide (d17:1/18:0)

C24 Ceramide (d17:1/24:0) Avanti Research™ - A Croda Brand 860649P, powder

Avanti

860649P

C24 Ceramide (d17:1/24:0)

C17 Ceramide (d18:1/17:0) Avanti Research™ - A Croda Brand

Avanti

860517P

C17 Ceramide (d18:1/17:0)

Sphingosine (d18:1) Avanti Research™ - A Croda Brand

Avanti

860490P

Sphingosine (d18:1)

17:0 SM (d18:1/17:0) Avanti Research™ - A Croda Brand 860585P, powder

Avanti

860585P

17:0 SM (d18:1/17:0)

Mina Mirzaian et al.
Clinica chimica acta; international journal of clinical chemistry, 459, 36-44 (2016-05-26)
We developed a mass spectrometric procedure to quantify sphingosine-1-phosphate (S1P) in biological materials. The use of newly synthesized (13)C5 C18-S1P and commercial C17-S1P as internal standards rendered very similar results with respect to linearity, limit of detection and limit of
Constantin Bode et al.
Methods in molecular biology (Clifton, N.J.), 874, 33-44 (2012-04-25)
Liquid chromatography coupled to tandem mass spectrometry has evolved as the method of choice for the detection of sphingolipid metabolites due to its high sensitivity and superior specificity compared to other methodological approaches. Here, we describe a simple and robust
Cecilia Frej et al.
Analytical and bioanalytical chemistry, 407(28), 8533-8542 (2015-09-18)
Sphingosine 1-phosphate (S1P) is a signalling sphingolipid affecting multiple cellular functions of vascular and immune systems. It circulates at submicromolar levels bound to HDL-associated apolipoprotein M (apoM) or to albumin. S1P in blood is mainly produced by platelets and erythrocytes
Eri Sakai et al.
The journal of applied laboratory medicine, 5(4), 656-670 (2020-05-15)
Sphingolipids have been demonstrated to be involved in many human diseases. However, measurement of sphingolipids, especially of sphingosine 1-phosphate (S1P) and dihydro-sphingosine 1-phosphate (dhS1P), in blood samples requires strict sampling, since blood cells easily secrete these substances during sampling and
Pernille M Christensen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(6), 2351-2359 (2016-03-10)
Apolipoprotein M (ApoM) transports sphingosine-1-phosphate (S1P) in plasma, and ApoM-deficient mice (Apom(-/-)) have ∼50% reduced plasma S1P levels. There are 5 known S1P receptors, and S1P induces adherens junction formation between endothelial cells through the S1P1 receptor, which in turn
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica