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790427P

Avanti

06:0 PC-d22

Avanti Research - A Croda Brand 790427P, powder

Sinônimo(s):

1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (Notação de Hill):
C20H18NO8PD22
Número CAS:
Peso molecular:
475.64
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

powder

embalagem

pkg of 1 × 10 mg (790427P-10mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 790427P

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) is a hydrophobic acyl chain containing phospholipid with a critical micelle concentration of 15 mM. 06:0 PC-d22 is the deuterated form of 06:0 PC.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Aplicação

06:0 PC-d22 has been used in small isotropic bicelles preparation for C-peptide membrane interaction studies by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY) and in in situ infrared (IR) absorption spectra. It may be used as an internal standard in capillary electrophoresis time of flight mass spectrometer (CE-TOFMS) and liquid chromatography with tandem mass spectrometry (LC-MS-MS) for the analysis of algal lipidome.

Ações bioquímicas/fisiológicas

1,2-dihexanoyl-sn-glycero-3-phosphocholine (06:0 PC) bicelle with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) takes a disc like conformation. Phosphocholine (PC) is the catabolized product of phosphatidylcholine (lecithin). PC mediates immune response and acts as a ligand for nicotinic acetylcholine receptors (nAChR).

Embalagem

5 mL Clear Glass Sealed Ampule (790427P-10mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids


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Sofia Unnerståle et al.
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012, 185907-185907 (2012-08-01)
C-peptide is the connecting peptide between the A and B chains of insulin in proinsulin. In this paper, we investigate the interaction between C-peptide and phospholipid bicelles, by circular dichroism and nuclear magnetic resonance spectroscopy, and in particular the pH
Takuro Ito et al.
Metabolomics : Official journal of the Metabolomic Society, 9(Suppl 1), 178-187 (2013-03-07)
Oil-rich algae have promising potential for a next-generation biofuel feedstock. Pseudochoricystis ellipsoidea MBIC 11204, a novel unicellular green algal strain, accumulates a large amount of oil (lipids) in nitrogen-deficient (-N) conditions. Although the oil bodies are easily visualized by lipophilic
Soichiro Matsunaga et al.
Langmuir : the ACS journal of surfaces and colloids, 33(46), 13157-13167 (2017-08-02)
In situ dynamic observation of model biological cell membranes, formed on a water/gold substrate interface, has been performed by the combination of electrochemical scanning tunneling microscopy and reflection infrared absorption vibrational spectroscopy. Monolayers of 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) were formed on alkanethiol-modified
K Richter et al.
Scientific reports, 6, 28660-28660 (2016-06-29)
We demonstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhibit ATP-dependent release of interleukin-1β from human and murine monocytes by a mechanism involving nicotinic acetylcholine receptors (nAChR). Interleukin-1β is a potent pro-inflammatory cytokine of innate immunity that plays pivotal roles
Systematic Characterization of DMPC/DHPC Self-Assemblies and Their Phase Behaviors in Aqueous Solution
Taguchi S, et al.
Colloids and Interfaces, 2(4), 73-73 (2018)

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