Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

700138P

Avanti

7-dehydrodesmosterol

powder

Sinônimo(s):

Cholesta-5,7,24-trien-3β-ol

Faça loginpara ver os preços organizacionais e de contrato

Selecione um tamanho

1 MG
R$ 3.864,00

R$ 3.864,00

Check Cart for Availability
Solicite uma grande encomenda
Todas as fotos(1)

Selecione um tamanho

Alterar visualização
1 MG
R$ 3.864,00

About This Item

Fórmula empírica (Notação de Hill):
C27H42O
Número CAS:
1715-86-2
Peso molecular:
382.62
Número MDL:
MFCD28359052
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 3.864,00

Check Cart for Availability
Solicite uma grande encomenda

Formulário

powder

embalagem

pkg of 1 × 1 mg (700138P-1mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 700138P

Condições de expedição

dry ice

temperatura de armazenamento

−70°C

cadeia de caracteres SMILES

O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@@H](CC[C@@H]4[C@@H](CCC=C(C)C)C)C3=CC=C2C1)C)C

InChI

1S/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9-10,19,21,23-25,28H,6,8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1

chave InChI

RUSSPKPUXDSHNC-DDPQNLDTSA-N

Descrição geral

7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step.[1]

Aplicação

7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).[2]

Ações bioquímicas/fisiológicas

7-dehydrodesmosterol (7-DHD) levels are higher during fetal development[3] and increases with aging.[4] Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model.[3] Reduced levels of 7-DHD is observed in shiverer and quaking disorder.[5]

Embalagem

5 mL Amber Glass Screw Cap Vial (700138P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Se precisar de ajuda, entre em contato Atendimento ao cliente

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 2

1 of 2

CHOLESTA-3,5-DIEN-7-ONE AldrichCPR

R209902

CHOLESTA-3,5-DIEN-7-ONE

5α-7,24-cholestadiene Avanti Research™ - A Croda Brand 700114P, powder

Avanti

700114P

5α-7,24-cholestadiene

J M Bourre et al.
Journal of neurochemistry, 54(4), 1196-1199 (1990-04-01)
In rat sciatic nerve, the 7-dehydrocholesterol content decreased dramatically during the postnatal period and slowly during adulthood and aging. In contrast, the 7-dehydrodesmosterol content peaked at 14 days and was nearly undetectable after 60 days. The desmosterol content peaked at
Alterations of cholesterol synthesis precursors (7-dehydrocholesterol, 7-dehydrodesmosterol, desmosterol) in dysmyelinating neurological mutant mouse (quaking, shiverer and trembler) in the PNS and the CNS
Bourre JM, et al.
Biochimica et Biophysica Acta, Lipids and Lipid Metabolism, 1004(3), 387-390 null
Anna Meljon et al.
Biochemical pharmacology, 86(1), 43-55 (2013-03-19)
In this study the sterol and oxysterol profile of newborn brain from the Dhcr7(Δ3-5/T93M) mouse model of Smith-Lemli-Opitz syndrome (SLOS) has been investigated. This is a viable mouse model which is compound heterozygous containing one null allele and one T93M
Vladimiro Cardenia et al.
Biochimie, 153, 99-108 (2018-08-06)
The electronic cigarettes (e-cigarettes, e-cigs) have become the most sought-after alternative to the traditional cigarettes, partly due to the widespread perception of safety. However, the high temperature reached by e-cig solutions can generate toxic compounds, some of which are listed
Josi Herron et al.
Current protocols in toxicology, 78(1), e65-e65 (2018-10-16)
Cholesterol and cholesterol-derived oxysterols are critical for embryonic development, synapse formation and function, and myelination, among other biological functions. Indeed, alterations in levels of cholesterol, sterol precursors, and oxysterols result in a variety of developmental disorders, emphasizing the importance of

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica