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57865

Sigma-Aldrich

4-Nitrophenyl iodoacetate

≥99.0%

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About This Item

Fórmula empírica (Notação de Hill):
C8H6INO4
Número CAS:
31252-85-4
Peso molecular:
307.04
Beilstein:
1970746
Número CE:
250-536-6
Número MDL:
MFCD00042813
Código UNSPSC:
12352100
ID de substância PubChem:
57651634
NACRES:
NA.22

Ensaio

≥99.0%

pf

79-82 °C

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[O-][N+](=O)c1ccc(OC(=O)CI)cc1

InChI

1S/C8H6INO4/c9-5-8(11)14-7-3-1-6(2-4-7)10(12)13/h1-4H,5H2

chave InChI

GERXSZLDSOPHJV-UHFFFAOYSA-N

Outras notas

For introducing the iodoacetyl group in peptides; Synthesis of N-methyl iodoacetamide

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

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K Sutoh et al.
Biochemistry, 27(8), 2964-2969 (1988-04-19)
Subfragment 1 (S1) prepared from rabbit skeletal muscle myosin was digested with trypsin to cleave the 95K heavy chain into three pieces, i.e., the 23K, 50K, and 20K fragments. The trypsin-treated S1 was then cross-linked with p-nitrophenyl iodoacetate. The cross-linker
T Hiratsuka
Biochemistry, 26(11), 3168-3173 (1987-06-02)
When myosin subfragment 1 (S-1) reacts with the bifunctional reagents with cross-linking spans of 3-4.5 A, p-nitrophenyl iodoacetate and p-nitrophenyl bromoacetate, the 20-kilodalton (20-kDa) segment of the heavy chain is cross-linked to the 26-kDa segment via the reactive thiol SH2.
U Ramseier et al.
Analytical biochemistry, 221(2), 231-233 (1994-09-01)
Cysteine residues derivatized with N-methyl iodoacetamide (MIAA) can be analyzed by the Edman sequencing with a high degree of reliability. By HPLC, the phenylthiohydantoin (PTH) derivative of MIAA-modified cysteine eluted between dimethylphenylthiourea and PTH-Ala--a wide gap which is not occupied
Synthesis and characterization of two fluorescent sulfhydryl reagents.
E N Hudson et al.
Biochemistry, 12(21), 4154-4161 (1973-10-09)
Ya Zhang et al.
International journal of nanomedicine, 7, 1015-1022 (2012-03-10)
Polymersomes are nanosized vesicles formed from amphiphilic block copolymers, and have been identified as potential drug delivery vehicles to the inner ear. The aim of this study was to provide targeting to specific cells within the inner ear by functionalizing

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